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SPYRE THERAPEUTICS INC

106.49

-1.3000-1.21%

Post-market: 106.490.00000.00%19:37 EDT

Volume:1.01M

Turnover:108.82M

Market Cap:9.39B

PE:-52.98

High:110.00

Open:108.85

Low:105.71

Close:107.79

52wk High:110.18

52wk Low:14.51

Shares:88.17M

Float Shares:80.98M

Volume Ratio:1.19

T/O Rate:1.25%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:9.83

PE(LYR):-53.91

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Overview Company News Filings

Spyre Therapeutics - Material Deal Triggers End of Dosing Restrictions Outside Initial Field After June 1, 2028 - SEC Filing

THOMSON REUTERS

Spyre Therapeutics shareholders approve amended employee stock purchase plan at annual meeting

Spyre Therapeutics to Present at Jefferies Global Healthcare Conference

Spyre Therapeutics to Participate in Upcoming June Investor Conferences

LifeSci Capital Sticks to Its Buy Rating for Spyre Therapeutics (SYRE)

Analysts Offer Insights on Healthcare Companies: Mereo Biopharma Group Plc (MREO), DocGo (DCGO) and Spyre Therapeutics (SYRE)

Spyre Therapeutics (SYRE) Receives a Rating Update from a Top Analyst

Spyre Therapeutics Director Michael Thomas Henderson sells USD 5.87 million common shares

Spyre Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

Jefferies Sticks to Its Buy Rating for Spyre Therapeutics (SYRE)

Spyre Therapeutics’ Exclusive Forum Clauses Shift Legal Leverage, Raise Venue and Litigation Cost Concerns for Stockholders

Analysts’ Top Healthcare Picks: Spyre Therapeutics (SYRE), uniQure (QURE)

Earnings Flash (SYRE) Spyre Therapeutics Posts Q1 Net Loss $0.74 a Share, vs. FactSet Est of $0.67 Loss

MT Newswires Live

Spyre Q1 FY26 net loss widens to $69 million; R&D expenses rise to $60.4 million

Spyre Therapeutics Inc - Reports Cash, Cash Equivalents, and Marketable Securities of $741.5 Mln as of March 31, 2026,Expected Runway Into H2 2029

THOMSON REUTERS

Spyre Therapeutics, Inc. Q1 Basic EPS USD -29.66

THOMSON REUTERS

Spyre Therapeutics, Inc. Q1 Operating Expenses USD 45.641 Million

THOMSON REUTERS

Corrected-Spyre Therapeutics, Inc. Q1 Basic EPS USD -0.74 (Corrects Amount)

THOMSON REUTERS

Press Release: Spyre Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Spyre Therapeutics CFO Scott Burrows disposes 12,500 shares worth $892,125

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Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 29, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260529:nNDL27v5pv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638903540","title":"Spyre Therapeutics to Present at Jefferies Global Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2638903540","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638903540?lang=en_us&edition=fundamental","pubTime":"2026-05-27 04:11","pubTimestamp":1779826285,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics will present at the Jefferies Global Healthcare Conference in New York on June 3, 2026.Management will also appear at the Goldman Sachs 47th Annual Global Healthcare Conference in Miami on June 8, 2026.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260526:nNDL1s0n7c:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1868836591.USD","LU2237443895.HKD","LU0096364046.USD","SG9999014005.SGD","LU0251131958.USD","LU2471134952.CNY","LU0345770993.USD","IE00BSNM7G36.USD","LU1868837136.USD","LU0742534661.SGD","IE00BGHQF748.EUR","LU2210149790.SGD","GSX","NDAQ","LU2237438978.USD","BK4550","IE00BN0W2V16.EUR","IE0002270589.USD","LU2471134796.USD","LU2210150020.SGD","IE00B19Z3581.USD","LU0048573561.USD","BK4127","IE00B3QW5Z07.USD","BK4585","LU0345770308.USD","LU2237443465.HKD","LU1868836914.USD","BK4552","LU0868494708.USD","IE00BN0W2T93.GBP","LU0251142724.SGD","LU1791807156.HKD","LU0314104364.USD","LU2237443622.USD","IE00BN0W2W23.USD","SG9999014013.SGD","BK4516","LU0942090050.USD","LU2237443382.USD","BK4588","LU2471134879.HKD","LU0106831901.USD","IE00B64PRP62.GBP","LU2237443978.SGD","LU1868836757.USD","SYRE","IE0034235188.USD","LU1894683264.USD","LU0868494617.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638540776","title":"Spyre Therapeutics to Participate in Upcoming June Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2638540776","media":"GlobeNewswire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638540776?lang=en_us&edition=fundamental","pubTime":"2026-05-27 04:10","pubTimestamp":1779826200,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., May  26, 2026  (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. 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Q1 Basic EPS USD -0.74 (Corrects Amount)","url":"https://stock-news.laohu8.com/highlight/detail?id=2633291015","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633291015?lang=en_us&edition=fundamental","pubTime":"2026-05-05 20:00","pubTimestamp":1777982403,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260505:nPLX964A3D:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633910697","title":"Press Release: Spyre Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2633910697","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633910697?lang=en_us&edition=fundamental","pubTime":"2026-05-05 20:00","pubTimestamp":1777982400,"startTime":"0","endTime":"0","summary":"Announced positive topline induction data from Part A of the Phase 2 SKYLINE trial of SPY001, demonstrating best-in-class efficacy potential and a safety profile consistent with the <ALPHA>4<BETA>7 class. Announced over-enrollment and acceleration of topline readout to the third quarter of 2026 of the rheumatoid arthritis  sub-study of the Phase 2 SKYWAY basket trial. Remain on track for 6 proof-of-concept readouts in 2026 across the SKYLINE and SKYWAY Phase 2 trials. Further strengthened the balance sheet with $463 million gross proceeds from an underwritten public offering of. $1.2 billion in pro forma cash, cash equivalents, and marketable securities as of March 31, 2026, with expected runway into the second half of 2029. The Company is pioneering long-acting antibodies and antibody combinations to redefine the standard of care in IBD and rheumatic diseases. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders: ulce","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LENZ","SYRE","BK4539","BK4130","RHI","BK4139","LU0054578231.USD","BK4588","BK4007","BK4533"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632629147","title":"Spyre Therapeutics CFO Scott Burrows disposes 12,500 shares worth $892,125","url":"https://stock-news.laohu8.com/highlight/detail?id=2632629147","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632629147?lang=en_us&edition=fundamental","pubTime":"2026-05-02 09:36","pubTimestamp":1777685762,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics CFO Scott L. Burrows sold 12,500 common shares on May 1 at USD 71.37.Burrows exercised stock options for 12,500 shares on May 1 at USD 14.5.Directly held common shares totaled 97,994 following transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 01, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260502:nNDL7Zk1Rz:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":8,"pageCount":4,"totalSize":155,"code":"91000000","status":"200"}]}}