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Septerna, Inc.

40.00

-0.7900-1.94%

Post-market: 40.000.00000.00%19:30 EDT

Volume:289.81K

Turnover:11.73M

Market Cap:1.87B

PE:-73.74

High:41.44

Open:41.44

Low:39.95

Close:40.79

52wk High:51.10

52wk Low:11.70

Shares:46.68M

Float Shares:22.90M

Volume Ratio:0.66

T/O Rate:1.27%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.5424

EPS(LYR):-1.1044

ROE:-6.34%

ROA:-7.13%

PB:4.83

PE(LYR):-36.22

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Overview Company News Filings

Septerna to present preclinical data on oral hypoparathyroidism drug SEP-479 at ENDO 2026

Septerna to present preclinical characterization of SEP-479

Septerna price target raised to $53 from $47 at Raymond James

Septerna Chief People Officer Samira Shaikhly disposes of common shares worth $174,850.67

Septerna Chief People Officer Samira Shaikhly disposes of 11,798 common shares worth $354,116

3 Unknown Small-Cap Stocks with ‘Strong Buy’ Ratings and Up to 70% Upside in 2026

Wells Fargo Sticks to Their Buy Rating for Septerna, Inc. (SEPN)

Stock Track | Septerna, Inc. Soars 5.05% Intraday on Strong Quarterly Earnings Beat

Earnings Update: Septerna, Inc. (NASDAQ:SEPN) Just Reported Its First-Quarter Results And Analysts Are Updating Their Forecasts

Simply Wall St.

Septerna Inc reports results for the quarter ended March 31 - Earnings Summary

Septerna Price Target Maintained With a $40.00/Share by HC Wainwright & Co.

Septerna reports Q1 EPS (19c), consensus (27c)

Septerna Q1 revenue rises sharply helped by Novo Nordisk collaboration

Septerna Q1 EPS $(0.19) Beats $(0.42) Estimate, Sales $26.523M Beat $16.938M Estimate

Benzinga Earnings

Septerna Q1 FY26 net loss narrows to $8.6 million; revenue rises to $26.5 million

Press Release: Septerna Highlights Business Progress and Reports First Quarter 2026 Financial Results

Septerna CEO presents at Bank of America Securities Health Care Conference

Septerna announces annual shareholder meeting

Septerna initiated with a Buy at Stifel

Is Septerna (SEPN) Quietly Redefining Its GPCR Strategy With This First-in-Human SEP-479 Trial?

Simply Wall St.

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id":"2641484774","title":"Septerna to present preclinical data on oral hypoparathyroidism drug SEP-479 at ENDO 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2641484774","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641484774?lang=en_us&edition=fundamental","pubTime":"2026-06-08 20:55","pubTimestamp":1780923356,"startTime":"0","endTime":"0","summary":"Septerna will present preclinical data on SEP-479 at the Endocrine Society’s ENDO 2026 meeting in Chicago on June 13-16, 2026.The oral presentation is scheduled for June 13, 2026, 2:15-2:30 p.m. CT.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief on June 08, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nNDLbnB2BG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641481071","title":"Septerna to present preclinical characterization of SEP-479","url":"https://stock-news.laohu8.com/highlight/detail?id=2641481071","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641481071?lang=en_us&edition=fundamental","pubTime":"2026-06-08 20:16","pubTimestamp":1780921015,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) announced that the first detailed preclinical characterization of SEP-479 has been accepted for an oral presentation at the 2026 En...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-to-present-preclinical-characterization-of-sep-479-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-to-present-preclinical-characterization-of-sep-479-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641263485","title":"Septerna price target raised to $53 from $47 at Raymond James","url":"https://stock-news.laohu8.com/highlight/detail?id=2641263485","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641263485?lang=en_us&edition=fundamental","pubTime":"2026-06-08 18:35","pubTimestamp":1780914953,"startTime":"0","endTime":"0","summary":"Raymond James raised the firm’s price target on Septerna (SEPN) to $53 from $47 and keeps a Strong Buy rating on the shares. The firm sees Septerna...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-53-from-47-at-raymond-james-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-53-from-47-at-raymond-james-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","RJF"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640187085","title":"Septerna Chief People Officer Samira Shaikhly disposes of common shares worth $174,850.67","url":"https://stock-news.laohu8.com/highlight/detail?id=2640187085","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640187085?lang=en_us&edition=fundamental","pubTime":"2026-06-04 07:12","pubTimestamp":1780528353,"startTime":"0","endTime":"0","summary":"Septerna Chief People Officer Samira Shaikhly reported selling 5,935 shares on June 1, 2026 at $27.78 to $29.66.She also exercised stock options the same day for 5,935 shares at $1.55 to $2.76 per share.Her directly held common stock position fell to 793 shares following the transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 03, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260603:nNDL9xx8nC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna Chief People Officer Samira Shaikhly disposes of common shares worth $174,850.67","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639614457","title":"Septerna Chief People Officer Samira Shaikhly disposes of 11,798 common shares worth $354,116","url":"https://stock-news.laohu8.com/highlight/detail?id=2639614457","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639614457?lang=en_us&edition=fundamental","pubTime":"2026-05-29 07:02","pubTimestamp":1780009353,"startTime":"0","endTime":"0","summary":"Septerna Chief People Officer Samira Shaikhly sold 11,798 common shares on May 26 at USD 30.06.She exercised stock options for 11,798 shares at USD 6.81 on the same day.Her direct common stock stake fell to 793 shares.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 28, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260528:nNDLtXggl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna Chief People Officer Samira Shaikhly disposes of 11,798 common shares worth $354,116","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638997543","title":"3 Unknown Small-Cap Stocks with ‘Strong Buy’ Ratings and Up to 70% Upside in 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2638997543","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638997543?lang=en_us&edition=fundamental","pubTime":"2026-05-26 22:33","pubTimestamp":1779806036,"startTime":"0","endTime":"0","summary":"Small-cap stocks often go unnoticed, but a few are grabbing Wall Street’s attention. Analysts are highlighting Septerna, Inc. ($SEPN), Kornit Digit...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-unknown-small-cap-stocks-with-strong-buy-ratings-and-up-to-70-upside-in-2026?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-unknown-small-cap-stocks-with-strong-buy-ratings-and-up-to-70-upside-in-2026?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636783180","title":"Wells Fargo Sticks to Their Buy Rating for Septerna, Inc. (SEPN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2636783180","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636783180?lang=en_us&edition=fundamental","pubTime":"2026-05-18 19:37","pubTimestamp":1779104269,"startTime":"0","endTime":"0","summary":"In a report released today, Derek Archila from Wells Fargo maintained a Buy rating on Septerna, Inc., with a price target of $48.00. According to T...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/wells-fargo-sticks-to-their-buy-rating-for-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/wells-fargo-sticks-to-their-buy-rating-for-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","PGF"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1142366590","title":"Stock Track | Septerna, Inc. Soars 5.05% Intraday on Strong Quarterly Earnings Beat","url":"https://stock-news.laohu8.com/highlight/detail?id=1142366590","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1142366590?lang=en_us&edition=fundamental","pubTime":"2026-05-14 23:58","pubTimestamp":1778774280,"startTime":"0","endTime":"0","summary":"Septerna, Inc.'s stock soared 5.05% during intraday trading on Thursday, following the release of its first-quarter results that significantly exceeded analyst expectations.The biopharmaceutical...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635749961","title":"Earnings Update: Septerna, Inc. (NASDAQ:SEPN) Just Reported Its First-Quarter Results And Analysts Are Updating Their Forecasts","url":"https://stock-news.laohu8.com/highlight/detail?id=2635749961","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635749961?lang=en_us&edition=fundamental","pubTime":"2026-05-14 21:57","pubTimestamp":1778767059,"startTime":"0","endTime":"0","summary":"As you might know, Septerna, Inc. ( NASDAQ:SEPN ) just kicked off its latest quarterly results with some very strong...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/earnings-update-septerna-inc-nasdaqsepn-just-reported-its-fi","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/earnings-update-septerna-inc-nasdaqsepn-just-reported-its-fi","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SEPN",".IXIC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635762781","title":"Septerna Inc reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2635762781","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635762781?lang=en_us&edition=fundamental","pubTime":"2026-05-13 19:59","pubTimestamp":1778673592,"startTime":"0","endTime":"0","summary":"Septerna Inc reports results for the quarter ended March 31 - Earnings SummarySepterna Inc SEPN.OQ reported a quarterly adjusted loss of 19 cents per share for the quarter ended March 31, higher than ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260513:nL8N41Q1HW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635978936","title":"Septerna Price Target Maintained With a $40.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2635978936","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635978936?lang=en_us&edition=fundamental","pubTime":"2026-05-13 19:17","pubTimestamp":1778671020,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  May 13, 2026 07:17 ET (11:17 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634253251","title":"Septerna reports Q1 EPS (19c), consensus (27c)","url":"https://stock-news.laohu8.com/highlight/detail?id=2634253251","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634253251?lang=en_us&edition=fundamental","pubTime":"2026-05-12 05:33","pubTimestamp":1778535222,"startTime":"0","endTime":"0","summary":"Reports Q1 revenue $26.52M, consensus $15.09M. “In the first quarter, we continued to make meaningful progress across our pipeline, highlighted by ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-reports-q1-eps-19c-consensus-27c-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-reports-q1-eps-19c-consensus-27c-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634258399","title":"Septerna Q1 revenue rises sharply helped by Novo Nordisk collaboration","url":"https://stock-news.laohu8.com/highlight/detail?id=2634258399","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634258399?lang=en_us&edition=fundamental","pubTime":"2026-05-12 04:52","pubTimestamp":1778532722,"startTime":"0","endTime":"0","summary":"Septerna Q1 revenue rises sharply helped by Novo Nordisk collaborationOverviewUS biotechnology firm's Q1 revenue rose sharply, beating analyst expectationsCompany posted a narrower net loss compared t","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nL1N41O137:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634872237","title":"Septerna Q1 EPS $(0.19) Beats $(0.42) Estimate, Sales $26.523M Beat $16.938M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2634872237","media":"Benzinga Earnings","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634872237?lang=en_us&edition=fundamental","pubTime":"2026-05-12 04:10","pubTimestamp":1778530228,"startTime":"0","endTime":"0","summary":"Septerna Q1 EPS $(0.19) Beats $(0.42) Estimate, Sales $26.523M Beat $16.938M Estimate","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/quote/SEPN","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Septerna Q1 EPS $(0.19) Beats $(0.42) Estimate, Sales $26.523M Beat $16.938M Estimate","news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634232102","title":"Septerna Q1 FY26 net loss narrows to $8.6 million; revenue rises to $26.5 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2634232102","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634232102?lang=en_us&edition=fundamental","pubTime":"2026-05-12 04:03","pubTimestamp":1778529807,"startTime":"0","endTime":"0","summary":"Septerna posted a net loss of $8.6 million, narrowing from a $21.5 million loss a year earlier.Revenue climbed to $26.5 million from $219,000, driven by the Novo Nordisk collaboration.R&D expenses rose to $29.5 million from $19.3 million, while G&A costs increased to $10.3 million from $6.9 million.Cash, cash equivalents, and marketable securities totaled $522.1 million, with runway expected to fund operations at least into 2029.Pipeline updates included positive Phase 1 data for SEP-631 supporting Phase 2 development, with a Phase 2b trial in chronic spontaneous urticaria targeted for the second half of 2026, while a Phase 1 study of SEP-479 was initiated with data expected in late 2026 or early 2027.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nNDLbVkN0f:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3QW5Z07.USD","IE00BN0W2W23.USD","BK4112","SG9999014039.USD","IE00BN0W2V16.EUR","BK4007","IE00BN0W2T93.GBP","IE00B64PRP62.GBP","SG9999014005.SGD","LU2095319765.USD","SG9999014013.SGD","LU2210150020.SGD","SG9999014021.USD","IE00BKPKM429.USD","LU0314104364.USD","IE00BGHQF748.EUR","SEPN","NDAQ","BK4585","BK4588","LU2210149790.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634547232","title":"Press Release: Septerna Highlights Business Progress and Reports First Quarter 2026 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2634547232","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634547232?lang=en_us&edition=fundamental","pubTime":"2026-05-12 04:01","pubTimestamp":1778529660,"startTime":"0","endTime":"0","summary":"Compelling Phase 1 Data for SEP-631  in Healthy Volunteers Support Phase 2b Development, Initially in Chronic Spontaneous Urticaria  in Second Half of 2026. Phase 1 Clinical Trial Initiated for SEP-479, Oral Small Molecule PTH1R Agonist for Hypoparathyroidism. Cash Position of $522.1 Million Expected to Support Operating Plans at Least into 2029. \"In the first quarter, we continued to make meaningful progress across our pipeline, highlighted by positive Phase 1 clinical results for SEP-631 and the initiation of our Phase 1 clinical trial for SEP-479,\" said Jeffrey Finer, M.D., Ph.D., chief executive officer and co-founder of Septerna. \"These advances further validate our Native Complex Platform and its ability to efficiently generate differentiated oral small molecules against historically challenging GPCR targets. As our clinical programs continue to advance, we believe Septerna is increasingly well positioned to unlock the broad therapeutic potential of GPCR-targeted medicines for pa","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PRGS","SEPN","BK4022","BK4097","BK4007","R","BK4232","GPCR","BK4599","LU2065732104.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633910345","title":"Septerna CEO presents at Bank of America Securities Health Care Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2633910345","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633910345?lang=en_us&edition=fundamental","pubTime":"2026-05-05 20:01","pubTimestamp":1777982504,"startTime":"0","endTime":"0","summary":"Septerna CEO Jeffrey Finer will present at Bank of America Securities Health Care Conference on May 12, 2026, at 5:00 p.m. PT in Las Vegas.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260505:nNDL7ZGp7P:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014005.SGD","IE00BN0W2W23.USD","LU2210149790.SGD","IE00B64PRP62.GBP","IE00BGHQF748.EUR","BK4588","IE00BN0W2T93.GBP","LU2095319765.USD","BK4112","NDAQ","SG9999014013.SGD","IE00B3QW5Z07.USD","BK4007","IE00BN0W2V16.EUR","IE00BKPKM429.USD","LU2210150020.SGD","SG9999014021.USD","LU0314104364.USD","SG9999014039.USD","SEPN","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632566138","title":"Septerna announces annual shareholder meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2632566138","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632566138?lang=en_us&edition=fundamental","pubTime":"2026-05-01 04:43","pubTimestamp":1777581782,"startTime":"0","endTime":"0","summary":"Septerna scheduled 2026 annual stockholder meeting for June 26, 2026 in virtual format.Vote set for election of two Class II directors to serve until 2029 annual meeting.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 30, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nNDL5B9SwS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632369661","title":"Septerna initiated with a Buy at Stifel","url":"https://stock-news.laohu8.com/highlight/detail?id=2632369661","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632369661?lang=en_us&edition=fundamental","pubTime":"2026-05-01 04:39","pubTimestamp":1777581584,"startTime":"0","endTime":"0","summary":"Stifel analyst Alex Thompson initiated coverage of Septerna (SEPN) with a Buy rating and $43 price target The firm is bullish on Septerna’s G prote...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-initiated-with-a-buy-at-stifel-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-initiated-with-a-buy-at-stifel-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SF","BK4127","SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629054139","title":"Is Septerna (SEPN) Quietly Redefining Its GPCR Strategy With This First-in-Human SEP-479 Trial?","url":"https://stock-news.laohu8.com/highlight/detail?id=2629054139","media":"Simply Wall St.","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629054139?lang=en_us&edition=fundamental","pubTime":"2026-04-22 01:09","pubTimestamp":1776791388,"startTime":"0","endTime":"0","summary":"Septerna, Inc. recently began dosing healthy volunteers in a randomized, placebo-controlled Phase 1 trial of SEP-479, an oral PTH1R agonist for hypoparathyroidism, using single-ascending and multiple-ascending dose designs to assess safety, tolerability, pharmacokinetics and pharmacodynamics.\nThis first-in-human study, which could enroll up to 150 participants and tracks biomarkers such as endogenous PTH and serum calcium, marks a key progression of Septerna’s GPCR-targeted pipeline into...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-quietly-redefining-its-gpcr-strategy-with-t","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-quietly-redefining-its-gpcr-strategy-with-t","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SEPN","BK4007","GPCR","BK4599"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":6,"pageCount":3,"totalSize":103,"code":"91000000","status":"200"}]}}