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UpStream Bio Inc.

7.13

+0.52007.87%

Volume:431.49K

Turnover:3.01M

Market Cap:390.52M

PE:-2.48

High:7.14

Open:6.68

Low:6.68

Close:6.61

52wk High:33.68

52wk Low:5.85

Shares:54.77M

Float Shares:46.68M

Volume Ratio:0.83

T/O Rate:0.92%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.8758

EPS(LYR):-2.6636

ROE:-46.05%

ROA:-30.28%

PB:1.44

PE(LYR):-2.68

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Overview Company News Filings

Upstream Bio CEO Makes Notable Move With Fresh Stock Sale

Buy Rating on UPB Driven by Robust Verekitug Phase 2 Data and Upcoming Phase 3 Catalysts in CRSwNP and Severe Asthma

Upstream Bio announces verekitug met the primary endpoint

BRIEF-Upstream Bio Says Primary Endpoint Showed Reduction of -1.95 in Nasal Polyp Score

Upstream Bio reports Phase 2 VIBRANT trial gains for verekitug in nasal polyps

Upstream Bio Presents Additional Analyses From the Phase 2 Vibrant Trial of Verekitug in Chronic Rhinosinusitis With Nasal Polyps at 2026 Aaaai Annual Meeting

THOMSON REUTERS

Upstream Bio Inc - Secondary Endpoints Showed Reduction in Nasal Congestion Score by -0.96

THOMSON REUTERS

Arbor Realty Trust Reports Fourth Quarter and Full Year 2025 Results and Declares Dividend of $0.30 per Share

Upstream Bio to Present New Phase 2 VIBRANT Verekitug Analyses at AAAAI Congress 2026 Late-Breaking Poster Session

Upstream Bio CEO Rand Sutherland to Present at TD Cowen Annual Health Care Conference and Leerink Partners Global Healthcare Conference

Press Release: MFA Financial, Inc. Announces Fourth Quarter and Full Year 2025 Financial Results

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Upstream Bio, Inc. has reported insider selling activity b...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/insider-trading/upstream-bio-ceo-makes-notable-move-with-fresh-stock-sale-insider-trading-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/insider-trading/upstream-bio-ceo-makes-notable-move-with-fresh-stock-sale-insider-trading-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616340040","title":"Buy Rating on UPB Driven by Robust Verekitug Phase 2 Data and Upcoming Phase 3 Catalysts in CRSwNP and Severe Asthma","url":"https://stock-news.laohu8.com/highlight/detail?id=2616340040","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616340040?lang=en_us&edition=fundamental","pubTime":"2026-03-03 20:55","pubTimestamp":1772542554,"startTime":"0","endTime":"0","summary":"J.P. Morgan analyst Tessa Romero has maintained their bullish stance on UPB stock, giving a Buy rating yesterday. Tessa Romero has given his Buy ra...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/buy-rating-on-upb-driven-by-robust-verekitug-phase-2-data-and-upcoming-phase-3-catalysts-in-crswnp-and-severe-asthma-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/buy-rating-on-upb-driven-by-robust-verekitug-phase-2-data-and-upcoming-phase-3-catalysts-in-crswnp-and-severe-asthma-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616878069","title":"Upstream Bio announces verekitug met the primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2616878069","media":"TIPRANKS","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616878069?lang=en_us&edition=fundamental","pubTime":"2026-03-02 00:35","pubTimestamp":1772382925,"startTime":"0","endTime":"0","summary":"Upstream Bio (UPB) presented additional data from the Phase 2 Vibrant clinical trial evaluating verekitug in participants with chronic rhinosinusit...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/upstream-bio-announces-verekitug-met-the-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/upstream-bio-announces-verekitug-met-the-primary-endpoint-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["UPB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616782016","title":"BRIEF-Upstream Bio Says Primary Endpoint Showed Reduction of -1.95 in Nasal Polyp Score","url":"https://stock-news.laohu8.com/highlight/detail?id=2616782016","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616782016?lang=en_us&edition=fundamental","pubTime":"2026-03-01 22:47","pubTimestamp":1772376426,"startTime":"0","endTime":"0","summary":"BRIEF-Upstream Bio Says Primary Endpoint Showed Reduction of -1.95 in Nasal Polyp ScoreMarch 1 (Reuters) - Upstream Bio Inc UPB.O:UPSTREAM BIO PRESENTS ADDITIONAL ANALYSES FROM THE PHASE 2 VIBRANT TRI","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABNVLKV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["UPB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616201618","title":"Upstream Bio reports Phase 2 VIBRANT trial gains for verekitug in nasal polyps","url":"https://stock-news.laohu8.com/highlight/detail?id=2616201618","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616201618?lang=en_us&edition=fundamental","pubTime":"2026-03-01 22:45","pubTimestamp":1772376320,"startTime":"0","endTime":"0","summary":"Upstream Bio Inc. reported additional analyses from its Phase 2 VIBRANT trial  evaluating verekitug in 81 adults with chronic rhinosinusitis with nasal polyps over 24 weeks. The new analyses adjusted for concomitant rescue therapy use using a worst-observation carried-forward approach and showed a placebo-adjusted reduction in endoscopic nasal polyp score of -1.95  and a reduction in nasal congestion score of -0.96  at week 24; the company also reiterated previously reported data showing a 76% reduction in the need for surgery or systemic corticosteroids versus placebo . These additional results were presented at the AAAAI 2026 Annual Meeting, and the company said planning has begun for Phase 3 trials in chronic rhinosinusitis with nasal polyps and severe asthma.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nNDL3YqRrf:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BGHQF748.EUR","BK4139","BK4588","IE00BKPKM429.USD","IE00B64PRP62.GBP","SG9999014005.SGD","SG9999014039.USD","LU0314104364.USD","LU2095319765.USD","NDAQ","SG9999014021.USD","BK4585","UPB","BK4112","LU2210149790.SGD","LU2210150020.SGD","IE00B3QW5Z07.USD","SG9999014013.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616820978","title":"Upstream Bio Presents Additional Analyses From the Phase 2 Vibrant Trial of Verekitug in Chronic Rhinosinusitis With Nasal Polyps at 2026 Aaaai Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2616820978","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616820978?lang=en_us&edition=fundamental","pubTime":"2026-03-01 22:45","pubTimestamp":1772376300,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABNVLKV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["UPB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616582016","title":"Upstream Bio Inc - 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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Upstream Bio Inc. published the original content used to generate this news brief on February 26, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260226:nNDL8pqyW8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["UPB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2614892720","title":"Upstream Bio CEO Rand Sutherland to Present at TD Cowen Annual Health Care Conference and Leerink Partners Global Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2614892720","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614892720?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:01","pubTimestamp":1772020874,"startTime":"0","endTime":"0","summary":"Upstream Bio CEO Rand Sutherland to Present at TD Cowen Annual Health Care Conference and Leerink Partners Global Healthcare Conference","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260225:nNDL20hPs3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210149790.SGD","SG9999014013.SGD","LU2095319765.USD","BK4112","BK4207","SG9999014005.SGD","BK4588","SG9999014021.USD","LU2210150020.SGD","IE00BGHQF748.EUR","IE00BKPKM429.USD","IE00B64PRP62.GBP","BK4585","LU0314104364.USD","NDAQ","BK4139","IE00B3QW5Z07.USD","UPB","MNSH","SG9999014039.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2612461254","title":"Press Release: MFA Financial, Inc. Announces Fourth Quarter and Full Year 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2612461254","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612461254?lang=en_us&edition=fundamental","pubTime":"2026-02-18 21:30","pubTimestamp":1771421400,"startTime":"0","endTime":"0","summary":"MFA Financial, Inc.  today provided its financial results for the fourth quarter and full year ended December 31, 2025:. --  MFA generated GAAP net income to common stockholders and participating. securities for the fourth quarter of $43.6 million, or $0.42 per basic. --  Distributable earnings, a non-GAAP financial measure, were $27.8. million, or $0.27 per basic common share. MFA paid a regular cash. dividend of $0.36 per common share on January 30, 2026.Economic book value, a non-GAAP financial measure, was $13.75 per common. --  MFA closed the quarter with unrestricted cash of $213.2 million.$136.5 million, or $1.31 per basic common share and $1.30 per diluted. common share, up from $86.4 million, or $0.83 per basic common share and. \"We continued to execute on our strategic initiatives during the fourth quarter,\" said Craig Knutson, MFA's Chief Executive Officer. \"We acquired $1.2 billion of Agency MBS and $443 million of Non-QM loans, and Lima One originated $226 million of new b","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["UPB","BK4139","BK4213","MFA","BK4110","CRT"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":4,"totalSize":71,"code":"91000000","status":"200"}]}}