US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Spruce Biosciences, Inc.

54.76

+3.186.17%

Volume:79.82K

Turnover:4.40M

Market Cap:157.38M

PE:-1.42

High:58.59

Open:53.50

Low:51.16

Close:51.58

52wk High:240.00

52wk Low:7.26

Shares:2.87M

Float Shares:2.29M

Volume Ratio:2.32

T/O Rate:3.49%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-38.4300

EPS(LYR):-50.8298

ROE:-105.98%

ROA:-40.03%

PB:1.88

PE(LYR):-1.08

Loading ...

Overview Company News Filings

Spruce Biosciences price target lowered to $170 from $180 at Citizens

Rpt-Spruce Biosciences FY Net Income USD -38.966 Million

THOMSON REUTERS

Spruce Biosciences Inc - to Offer and Sell Common Stock up to $75 Mln Through Jefferies - SEC Filing

THOMSON REUTERS

Spruce Biosciences Inc - May Offer and Sell Common Stock up to Maximum Program Amount Under Sales Agreement - SEC Filing

THOMSON REUTERS

Spruce Biosciences Inc - Enters Open Market Sale Agreement With Jefferies Llc on March 9, 2026 - SEC Filing

THOMSON REUTERS

BRIEF-Spruce Biosciences Reports Full Year 2025 Financial Results

Spruce Biosciences 2025 net loss narrows, secures $50 mln funding

Spruce Biosciences FY 2025 R&D expenses fall 58% to USD 19.52 million, net loss narrows 27% to USD 38.97 million

Spruce Biosciences Inc - Expects Cash and Cash Equivalents to Fund Current Operating Plan Into Early 2027

THOMSON REUTERS

Spruce Biosciences Inc - Bla Submission for Ta-Ert for Treatment of Sanfilippo Syndrome Type B (Mps Iiib) on Track for Q4 2026

THOMSON REUTERS

Spruce Biosciences Inc - Net Loss $39.0 Mln for Year Ended Dec 31, 2025

THOMSON REUTERS

Press Release: Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates

Spruce Biosciences names Dale Hooks chief commercial officer

Spruce Biosciences Appoints Dale Hooks, an Accomplished Rare Disease Commercial Leader, as Chief Commercial Officer

THOMSON REUTERS

Spruce Biosciences CEO Javier Szwarcberg to Present at Leerink Global Healthcare Conference and The Citizens Life Sciences Conference

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers HK | Online Trading in stocks, bonds & ETFS","description":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","keywords":"tiger trading,tiger security,tiger broker hk,tigers co ltd,tiger trade hk,tiger brokers hk,stock broker,securities broker,online brokerage,hong kong broker,hk broker,online stock trading,online trading platform,stock trading platforms,trading application,stock trading,stock trading hong kong,buying stocks in hong kong,tiger brokers","social":{"ogDescription":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.gotigerhk.com/stock/SPRB/news?page=5"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"HKG","license":"TBHK","edition":"fundamental","symbol":"SPRB","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SPRB\",,,,,undefined,":{"symbol":"SPRB","market":"US","secType":"STK","nameCN":"Spruce Biosciences, Inc.","latestPrice":54.76,"timestamp":1787592613230,"preClose":51.58,"halted":0,"volume":79816,"delay":0,"changeRate":0.06165180302442807,"floatShares":2286500,"shares":2874013,"eps":-38.43,"marketStatus":"Trading","change":3.18,"latestTime":"08-24 13:30:29 EDT","open":53.5,"high":58.59,"low":51.16,"amount":4395812.7232800005,"amplitude":0.144048,"askPrice":56.73,"askSize":220,"bidPrice":54.5,"bidSize":94,"shortable":3,"etf":0,"ttmEps":-38.43,"tradingStatus":2,"nextMarketStatus":{"tag":"Post-Mkt","tradingStatus":3,"beginTime":1787601600000},"marketStatusCode":2,"adr":0,"listingDate":1602216000000,"exchange":"NASDAQ","adjPreClose":51.58,"preHourTrading":{"tag":"盘前","latestPrice":53.41,"preClose":51.58,"latestTime":"09:29 EDT","volume":6634,"amount":359087.49380199995,"timestamp":1787578199992,"change":1.83,"changeRate":0.035479,"amplitude":0.074835},"postHourTrading":{"tag":"盘后","latestPrice":51.58,"preClose":51.58,"latestTime":"19:30 EDT","volume":40,"amount":2039.88,"timestamp":1787355006894,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":2.31891,"impliedVol":0.883,"impliedVolPercentile":0},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"SPRB\",,,,,undefined,":{"symbol":"SPRB","floatShares":2286500,"roa":"-40.03%","roe":"-105.98%","lyrEps":-50.829769,"volumeRatio":2.31891,"shares":2874013,"dividePrice":0,"high":58.59,"amplitude":0.144048,"preClose":51.58,"low":51.16,"week52Low":7.26,"pbRate":"1.88","psRate":"225.80","week52High":240,"institutionHeld":0,"latestPrice":54.76,"committee":-0.401274,"eps":-38.43,"divideRate":0,"volume":79816,"delay":0,"ttmEps":-38.43,"open":53.5,"prevYearClose":87.11,"prevWeekClose":51.58,"prevMonthClose":42.83,"prevQuarterClose":54,"fiveDayClose":52.92,"twentyDayClose":41.99,"sixtyDayClose":49.19},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/SPRB\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-12","symbol":"SPRB","fiscalQuarterEnding":"2026/06","expectedEps":-4.79,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1786507200000,"reportTimeType":"pre","actualEps":-6.68},{"market":"US","date":"2026-05-13","symbol":"SPRB","fiscalQuarterEnding":"2026/03","expectedEps":-7.32,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1778644800000,"reportTimeType":"pre","actualEps":-8.94},{"market":"US","date":"2026-03-09","symbol":"SPRB","fiscalQuarterEnding":"2025/12","expectedEps":-12.87,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1773028800000,"reportTimeType":"pre","actualEps":-9.58},{"market":"US","date":"2025-11-10","symbol":"SPRB","fiscalQuarterEnding":"2025/09","expectedEps":-15.56,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1762750800000,"reportTimeType":"post","actualEps":-14.58},{"market":"US","date":"2025-08-07","symbol":"SPRB","defaultRemindTime":1754573400000,"type":"split","dateTimestamp":1754539200000,"forFactor":75,"toFactor":1,"ratio":75}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"SPRB\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"SPRB\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.375,"buy":0.625,"hold":0,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.625,"analysts":8,"updateTime":1784001600000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/SPRB\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"SPRB","date":"2026-08-21","current":-1.509238,"percent":0.131957,"low":-4.919282,"twenty":-2.221734,"median":-1.310679,"eighty":-0.563384,"high":-0.090272,"avg":-1.558383,"sd":1.100251,"marketCap":149405565},"quantilePoints":[{"date":"2021-08-27","current":-4.629913,"twenty":-22.144505,"median":-16.646596,"eighty":-7.540173,"marketCap":183279733},{"date":"2021-09-03","current":-4.65944,"twenty":-22.092278,"median":-13.658956,"eighty":-7.207839,"marketCap":184448609},{"date":"2021-09-10","current":-4.612196,"twenty":-21.979701,"median":-13.4578,"eighty":-7.17515,"marketCap":182578407},{"date":"2021-09-17","current":-4.192906,"twenty":-21.855929,"median":-13.284252,"eighty":-7.018518,"marketCap":165980370},{"date":"2021-09-24","current":-3.702749,"twenty":-21.774909,"median":-13.173813,"eighty":-6.761095,"marketCap":146577031},{"date":"2021-10-01","current":-3.342514,"twenty":-21.699717,"median":-13.094928,"eighty":-6.608548,"marketCap":132316746},{"date":"2021-10-08","current":-3.05905,"twenty":-21.66885,"median":-12.799108,"eighty":-6.430122,"marketCap":121095538},{"date":"2021-10-15","current":-2.645665,"twenty":-21.623151,"median":-12.700502,"eighty":-5.912553,"marketCap":104731276},{"date":"2021-10-22","current":-2.580704,"twenty":-21.578491,"median":-12.594008,"eighty":-5.273349,"marketCap":102159749},{"date":"2021-10-29","current":-2.811019,"twenty":-21.557581,"median":-12.519067,"eighty":-4.75511,"marketCap":111276980},{"date":"2021-11-05","current":-2.76968,"twenty":-21.535604,"median":-12.353408,"eighty":-4.668889,"marketCap":109640554},{"date":"2021-11-12","current":-2.639759,"twenty":-21.483148,"median":-12.2903,"eighty":-4.627551,"marketCap":104497500},{"date":"2021-11-19","current":-1.658709,"twenty":-21.403039,"median":-12.187749,"eighty":-4.529519,"marketCap":68746850},{"date":"2021-11-26","current":-1.556809,"twenty":-21.347853,"median":-11.962927,"eighty":-4.499992,"marketCap":64523494},{"date":"2021-12-03","current":-1.319042,"twenty":-21.303089,"median":-11.682884,"eighty":-4.40196,"marketCap":54668997},{"date":"2021-12-10","current":-1.426603,"twenty":-21.204942,"median":-11.048295,"eighty":-4.214166,"marketCap":59126984},{"date":"2021-12-17","current":-2.847545,"twenty":-21.080478,"median":-10.385445,"eighty":-3.762985,"marketCap":118019337},{"date":"2021-12-23","current":-2.105938,"twenty":-21.052665,"median":-10.330963,"eighty":-3.623615,"marketCap":87282691},{"date":"2021-12-31","current":-2.524861,"twenty":-20.969942,"median":-9.997267,"eighty":-3.361412,"marketCap":104645376},{"date":"2022-01-07","current":-2.185193,"twenty":-20.898638,"median":-9.62271,"eighty":-3.09094,"marketCap":90567523},{"date":"2022-01-14","current":-1.941765,"twenty":-20.867886,"median":-9.289014,"eighty":-2.870074,"marketCap":80478395},{"date":"2022-01-21","current":-1.46057,"twenty":-20.786782,"median":-9.135786,"eighty":-2.816924,"marketCap":60534769},{"date":"2022-01-28","current":-1.341686,"twenty":-20.748623,"median":-8.56714,"eighty":-2.76968,"marketCap":55607520},{"date":"2022-02-04","current":-1.290736,"twenty":-20.720004,"median":-8.373051,"eighty":-2.687003,"marketCap":53495842},{"date":"2022-02-11","current":-1.228464,"twenty":-20.672306,"median":-8.219824,"eighty":-2.669287,"marketCap":50914903},{"date":"2022-02-18","current":-1.205819,"twenty":-20.634148,"median":-7.974659,"eighty":-2.639759,"marketCap":49976379},{"date":"2022-02-25","current":-1.285075,"twenty":-20.59599,"median":-7.892938,"eighty":-2.594878,"marketCap":53261212},{"date":"2022-03-04","current":-1.132225,"twenty":-20.584093,"median":-7.634153,"eighty":-2.470514,"marketCap":46926178},{"date":"2022-03-11","current":-1.081274,"twenty":-20.582116,"median":-7.521786,"eighty":-2.378804,"marketCap":44814499},{"date":"2022-03-18","current":-1.110984,"twenty":-20.570251,"median":-7.232355,"eighty":-2.212367,"marketCap":46985746},{"date":"2022-03-25","current":-1.116539,"twenty":-20.552108,"median":-7.18809,"eighty":-2.013095,"marketCap":47220674},{"date":"2022-04-01","current":-1.183198,"twenty":-20.517765,"median":-7.171064,"eighty":-1.87836,"marketCap":50039819},{"date":"2022-04-08","current":-1.116539,"twenty":-20.502502,"median":-7.068912,"eighty":-1.663238,"marketCap":47220674},{"date":"2022-04-14","current":-1.177643,"twenty":-20.483423,"median":-6.93271,"eighty":-1.560206,"marketCap":49804890},{"date":"2022-04-22","current":-1.122094,"twenty":-20.464632,"median":-6.769267,"eighty":-1.500197,"marketCap":47455603},{"date":"2022-04-29","current":-0.977666,"twenty":-20.436887,"median":-6.714785,"eighty":-1.46057,"marketCap":41347456},{"date":"2022-05-06","current":-0.894342,"twenty":-20.383162,"median":-6.571773,"eighty":-1.441322,"marketCap":37823525},{"date":"2022-05-13","current":-0.723398,"twenty":-20.283091,"median":-6.476431,"eighty":-1.413017,"marketCap":31950307},{"date":"2022-05-20","current":-0.718079,"twenty":-20.20929,"median":-6.272127,"eighty":-1.389239,"marketCap":31715378},{"date":"2022-05-27","current":-0.755312,"twenty":-20.068537,"median":-5.900975,"eighty":-1.348479,"marketCap":33359879},{"date":"2022-06-03","current":-0.877652,"twenty":-19.985455,"median":-5.768178,"eighty":-1.314512,"marketCap":38763240},{"date":"2022-06-10","current":-0.824461,"twenty":-19.974008,"median":-4.919282,"eighty":-1.302058,"marketCap":36413953},{"date":"2022-06-17","current":-0.808503,"twenty":-19.949205,"median":-4.81003,"eighty":-1.281678,"marketCap":35709166},{"date":"2022-06-24","current":-0.882971,"twenty":-19.935849,"median":-4.71259,"eighty":-1.24205,"marketCap":38998169},{"date":"2022-07-01","current":-0.904247,"twenty":-19.92631,"median":-4.671251,"eighty":-1.219406,"marketCap":39937884},{"date":"2022-07-08","current":-1.010629,"twenty":-19.918678,"median":-4.65944,"eighty":-1.205418,"marketCap":44636458},{"date":"2022-07-15","current":-1.00531,"twenty":-19.851901,"median":-4.62696,"eighty":-1.188836,"marketCap":44401529},{"date":"2022-07-22","current":-1.058501,"twenty":-19.775584,"median":-4.547236,"eighty":-1.177643,"marketCap":46750817},{"date":"2022-07-29","current":-0.984034,"twenty":-19.736171,"median":-4.526566,"eighty":-1.160979,"marketCap":43461815},{"date":"2022-08-05","current":-1.117011,"twenty":-19.669527,"median":-4.488181,"eighty":-1.149869,"marketCap":49335033},{"date":"2022-08-12","current":-1.064485,"twenty":-19.613411,"median":-4.417315,"eighty":-1.133204,"marketCap":47120500},{"date":"2022-08-19","current":-1.165611,"twenty":-19.460778,"median":-4.387787,"eighty":-1.132225,"marketCap":51596947},{"date":"2022-08-26","current":-1.115048,"twenty":-19.41308,"median":-4.21948,"eighty":-1.122094,"marketCap":49358723},{"date":"2022-09-02","current":-1.048518,"twenty":-19.355842,"median":-3.856292,"eighty":-1.117709,"marketCap":46413692},{"date":"2022-09-09","current":-0.958037,"twenty":-19.34821,"median":-3.755899,"eighty":-1.116539,"marketCap":42408450},{"date":"2022-09-16","current":-0.904812,"twenty":-19.193668,"median":-3.628931,"eighty":-1.109077,"marketCap":40052425},{"date":"2022-09-23","current":-0.729172,"twenty":-19.102088,"median":-3.549206,"eighty":-1.088588,"marketCap":32277542},{"date":"2022-09-30","current":-0.729172,"twenty":-19.065839,"median":-3.348419,"eighty":-1.077655,"marketCap":32277542},{"date":"2022-10-07","current":-0.670626,"twenty":-18.815901,"median":-3.218498,"eighty":-1.064485,"marketCap":29685915},{"date":"2022-10-14","current":-0.606757,"twenty":-18.571687,"median":-3.011806,"eighty":-1.059031,"marketCap":26858685},{"date":"2022-10-21","current":-0.580144,"twenty":-18.472475,"median":-2.864168,"eighty":-1.052249,"marketCap":25680672},{"date":"2022-10-28","current":-0.617401,"twenty":-18.405698,"median":-2.829404,"eighty":-1.042544,"marketCap":27329890},{"date":"2022-11-04","current":-0.542887,"twenty":-18.38782,"median":-2.793302,"eighty":-1.025445,"marketCap":24031455},{"date":"2022-11-11","current":-0.618044,"twenty":-18.386689,"median":-2.76968,"eighty":-1.010629,"marketCap":27329890},{"date":"2022-11-18","current":-0.580748,"twenty":-18.38358,"median":-2.70472,"eighty":-0.998843,"marketCap":25680672},{"date":"2022-11-25","current":-0.580748,"twenty":-18.37708,"median":-2.687003,"eighty":-0.989724,"marketCap":25680672},{"date":"2022-12-02","current":-0.612716,"twenty":-17.812335,"median":-2.675193,"eighty":-0.983709,"marketCap":27094287},{"date":"2022-12-09","current":-0.543452,"twenty":-17.358251,"median":-2.65157,"eighty":-0.972881,"marketCap":24031455},{"date":"2022-12-16","current":-0.564764,"twenty":-17.00147,"median":-2.639759,"eighty":-0.962757,"marketCap":24973865},{"date":"2022-12-23","current":-0.57542,"twenty":-16.70765,"median":-2.598421,"eighty":-0.95567,"marketCap":25445070},{"date":"2022-12-30","current":-0.584691,"twenty":-15.658219,"median":-2.568893,"eighty":-0.936162,"marketCap":25855018},{"date":"2023-01-06","current":-1.289367,"twenty":-14.095191,"median":-2.482402,"eighty":-0.930959,"marketCap":57015805},{"date":"2023-01-13","current":-1.470518,"twenty":-13.727587,"median":-2.403147,"eighty":-0.932372,"marketCap":65026290},{"date":"2023-01-20","current":-1.363958,"twenty":-13.544573,"median":-2.372011,"eighty":-0.936162,"marketCap":60314240},{"date":"2023-01-27","current":-1.561093,"twenty":-13.465688,"median":-2.287094,"eighty":-0.936162,"marketCap":69031532},{"date":"2023-02-03","current":-1.550437,"twenty":-13.449911,"median":-2.179532,"eighty":-0.942069,"marketCap":68560327},{"date":"2023-02-10","current":-1.483736,"twenty":-13.34736,"median":-2.01536,"eighty":-0.952119,"marketCap":65610791},{"date":"2023-02-17","current":-1.371655,"twenty":-13.284252,"median":-1.97007,"eighty":-0.958037,"marketCap":60654580},{"date":"2023-02-24","current":-1.977419,"twenty":-13.259009,"median":-1.959592,"eighty":-0.958037,"marketCap":87441455},{"date":"2023-03-03","current":-2.157184,"twenty":-13.18959,"median":-1.998376,"eighty":-0.960408,"marketCap":95390678},{"date":"2023-03-10","current":-2.103254,"twenty":-13.173813,"median":-2.027849,"eighty":-0.962406,"marketCap":93005911},{"date":"2023-03-17","current":-1.996773,"twenty":-13.142259,"median":-2.031348,"eighty":-0.962757,"marketCap":92210989},{"date":"2023-03-24","current":-1.936526,"twenty":-13.102816,"median":-2.001206,"eighty":-0.967012,"marketCap":89428761},{"date":"2023-03-31","current":-1.902099,"twenty":-12.87405,"median":-1.988166,"eighty":-0.968076,"marketCap":87838916},{"date":"2023-04-06","current":-1.910705,"twenty":-12.81883,"median":-1.97956,"eighty":-0.970497,"marketCap":88236377},{"date":"2023-04-14","current":-1.686929,"twenty":-12.795164,"median":-1.970953,"eighty":-0.972881,"marketCap":77902387},{"date":"2023-04-21","current":-1.816031,"twenty":-12.746256,"median":-1.950454,"eighty":-0.973395,"marketCap":83864304},{"date":"2023-04-28","current":-1.790211,"twenty":-12.709968,"median":-1.941297,"eighty":-0.975958,"marketCap":82671921},{"date":"2023-05-05","current":-2.022594,"twenty":-12.695769,"median":-1.936526,"eighty":-0.980999,"marketCap":93403372},{"date":"2023-05-12","current":-1.919312,"twenty":-12.650016,"median":-1.941297,"eighty":-0.983709,"marketCap":88633838},{"date":"2023-05-19","current":-1.902735,"twenty":-12.588486,"median":-1.936412,"eighty":-0.984034,"marketCap":89826222},{"date":"2023-05-26","current":-1.902735,"twenty":-12.537999,"median":-1.938677,"eighty":-0.987225,"marketCap":89826222},{"date":"2023-06-02","current":-1.95325,"twenty":-12.519067,"median":-1.943449,"eighty":-0.989353,"marketCap":92210989},{"date":"2023-06-09","current":-1.961669,"twenty":-12.506445,"median":-1.95325,"eighty":-0.9896,"marketCap":92608450},{"date":"2023-06-16","current":-1.986927,"twenty":-12.452803,"median":-1.953494,"eighty":-0.991851,"marketCap":93800833},{"date":"2023-06-23","current":-1.85222,"twenty":-12.381807,"median":-1.951852,"eighty":-0.994672,"marketCap":87441455},{"date":"2023-06-30","current":-1.784867,"twenty":-12.306077,"median":-1.947793,"eighty":-0.994672,"marketCap":84261765},{"date":"2023-07-07","current":-1.784867,"twenty":-12.296611,"median":-1.944831,"eighty":-0.9978,"marketCap":84261765},{"date":"2023-07-14","current":-1.768028,"twenty":-12.2903,"median":-1.938677,"eighty":-1.00314,"marketCap":83466843},{"date":"2023-07-21","current":-1.869058,"twenty":-12.285567,"median":-1.936412,"eighty":-1.00531,"marketCap":88236377},{"date":"2023-07-28","current":-1.85222,"twenty":-12.244546,"median":-1.923652,"eighty":-1.008501,"marketCap":87441455},{"date":"2023-08-04","current":-1.986927,"twenty":-12.181438,"median":-1.927993,"eighty":-1.010629,"marketCap":93800833},{"date":"2023-08-11","current":-1.911154,"twenty":-12.061533,"median":-1.915233,"eighty":-1.01382,"marketCap":90223683},{"date":"2023-08-18","current":-1.9696,"twenty":-11.955827,"median":-1.911154,"eighty":-1.016329,"marketCap":94855912},{"date":"2023-08-25","current":-1.859708,"twenty":-11.851698,"median":-1.910705,"eighty":-1.016583,"marketCap":89563522},{"date":"2023-08-31","current":-1.880841,"twenty":-11.753881,"median":-1.905267,"eighty":-1.021014,"marketCap":90581289},{"date":"2023-09-08","current":-1.885067,"twenty":-11.681306,"median":-1.902735,"eighty":-1.02766,"marketCap":90784843},{"date":"2023-09-15","current":-2.071038,"twenty":-11.648175,"median":-1.907798,"eighty":-1.028509,"marketCap":99741195},{"date":"2023-09-20","current":-2.054132,"twenty":-11.621354,"median":-1.909252,"eighty":-1.029358,"marketCap":98926981},{"date":"2023-09-29","current":-1.885067,"twenty":-11.567712,"median":-1.909252,"eighty":-1.031057,"marketCap":90784843},{"date":"2023-10-05","current":-1.716003,"twenty":-11.146814,"median":-1.902735,"eighty":-1.036161,"marketCap":82642704},{"date":"2023-10-13","current":-1.394781,"twenty":-10.555698,"median":-1.902417,"eighty":-1.042544,"marketCap":67172641},{"date":"2023-10-20","current":-0.99748,"twenty":-10.506665,"median":-1.902099,"eighty":-1.040416,"marketCap":48038616},{"date":"2023-10-27","current":-0.904494,"twenty":-10.494407,"median":-1.902099,"eighty":-1.031906,"marketCap":43560440},{"date":"2023-10-31","current":-0.94676,"twenty":-10.450822,"median":-1.901974,"eighty":-1.02766,"marketCap":45595975},{"date":"2023-11-10","current":-0.896041,"twenty":-10.382721,"median":-1.898145,"eighty":-1.012757,"marketCap":43153333},{"date":"2023-11-17","current":-1.110751,"twenty":-10.359566,"median":-1.894316,"eighty":-1.00531,"marketCap":54552327},{"date":"2023-11-24","current":-1.177065,"twenty":-10.315981,"median":-1.885067,"eighty":-1.006374,"marketCap":57809182},{"date":"2023-12-01","current":-1.160486,"twenty":-10.215191,"median":-1.884976,"eighty":-1.010629,"marketCap":56994968},{"date":"2023-12-08","current":-1.201932,"twenty":-10.029956,"median":-1.880841,"eighty":-1.011693,"marketCap":59030503},{"date":"2023-12-15","current":-1.392584,"twenty":-9.888305,"median":-1.874941,"eighty":-1.016075,"marketCap":68393962},{"date":"2023-12-22","current":-1.699284,"twenty":-9.660847,"median":-1.869058,"eighty":-1.016583,"marketCap":83456918},{"date":"2023-12-29","current":-2.362419,"twenty":-9.632244,"median":-1.869058,"eighty":-1.016583,"marketCap":116025472},{"date":"2024-01-05","current":-2.387286,"twenty":-9.579125,"median":-1.873268,"eighty":-1.021014,"marketCap":117246792},{"date":"2024-01-12","current":-2.204924,"twenty":-9.478335,"median":-1.877478,"eighty":-1.02766,"marketCap":108290440},{"date":"2024-01-19","current":-1.989405,"twenty":-9.336685,"median":-1.884885,"eighty":-1.02766,"marketCap":97705660},{"date":"2024-01-26","current":-2.528203,"twenty":-9.241343,"median":-1.885067,"eighty":-1.031906,"marketCap":124167610},{"date":"2024-02-02","current":-2.851481,"twenty":-9.200482,"median":-1.885067,"eighty":-1.042544,"marketCap":140044780},{"date":"2024-02-09","current":-3.299097,"twenty":-9.07109,"median":-1.894316,"eighty":-1.042544,"marketCap":162028554},{"date":"2024-02-16","current":-4.194329,"twenty":-8.723773,"median":-1.901974,"eighty":-1.043195,"marketCap":205996101},{"date":"2024-02-23","current":-4.443005,"twenty":-8.598467,"median":-1.902099,"eighty":-1.044099,"marketCap":218209309},{"date":"2024-03-01","current":-4.144594,"twenty":-8.561692,"median":-1.902417,"eighty":-1.047679,"marketCap":203553460},{"date":"2024-03-08","current":-4.467873,"twenty":-8.47316,"median":-1.907798,"eighty":-1.052249,"marketCap":219430629},{"date":"2024-03-15","current":-0.694063,"twenty":-8.326062,"median":-1.910705,"eighty":-1.052249,"marketCap":33258781},{"date":"2024-03-22","current":-0.648765,"twenty":-8.272943,"median":-1.902735,"eighty":-1.042544,"marketCap":31088190},{"date":"2024-03-28","current":-0.635455,"twenty":-8.238892,"median":-1.902099,"eighty":-1.02766,"marketCap":30450378},{"date":"2024-04-05","current":-0.720726,"twenty":-8.203479,"median":-1.902036,"eighty":-1.01382,"marketCap":34536489},{"date":"2024-04-12","current":-0.65569,"twenty":-8.094517,"median":-1.901974,"eighty":-1.00314,"marketCap":31420022},{"date":"2024-04-19","current":-0.602016,"twenty":-7.963763,"median":-1.894316,"eighty":-0.992792,"marketCap":28847983},{"date":"2024-04-26","current":-0.602016,"twenty":-7.920178,"median":-1.885067,"eighty":-0.984034,"marketCap":28847983},{"date":"2024-05-03","current":-0.636883,"twenty":-7.887489,"median":-1.884976,"eighty":-0.973395,"marketCap":30518780},{"date":"2024-05-10","current":-0.720014,"twenty":-7.747201,"median":-1.880841,"eighty":-0.965948,"marketCap":34502353},{"date":"2024-05-17","current":-0.677676,"twenty":-7.647773,"median":-1.874941,"eighty":-0.958037,"marketCap":31683399},{"date":"2024-05-24","current":-0.638717,"twenty":-7.589206,"median":-1.869058,"eighty":-0.94676,"marketCap":29861922},{"date":"2024-05-31","current":-0.636956,"twenty":-7.556518,"median":-1.863368,"eighty":-0.936162,"marketCap":29779612},{"date":"2024-06-07","current":-0.593295,"twenty":-7.527915,"median":-1.859708,"eighty":-0.92894,"marketCap":27738334},{"date":"2024-06-14","current":-0.591623,"twenty":-7.487054,"median":-1.85222,"eighty":-0.925627,"marketCap":27660140},{"date":"2024-06-21","current":-0.466538,"twenty":-7.47071,"median":-1.851737,"eighty":-0.912947,"marketCap":21812043},{"date":"2024-06-28","current":-0.468474,"twenty":-7.375368,"median":-1.851254,"eighty":-0.904621,"marketCap":21902584},{"date":"2024-07-05","current":-0.497347,"twenty":-7.228269,"median":-1.847027,"eighty":-0.897682,"marketCap":23252461},{"date":"2024-07-12","current":-0.49946,"twenty":-7.207839,"median":-1.835382,"eighty":-0.887728,"marketCap":23351232},{"date":"2024-07-15","current":-0.506061,"twenty":-7.203753,"median":-1.835382,"eighty":-0.884818,"marketCap":23659893},{"date":"2024-08-02","current":-0.439954,"twenty":-7.199667,"median":-1.835382,"eighty":-0.882971,"marketCap":20569168},{"date":"2024-08-09","current":-0.391188,"twenty":-7.187409,"median":-1.825895,"eighty":-0.865363,"marketCap":18289192},{"date":"2024-08-16","current":-0.421457,"twenty":-7.180598,"median":-1.818543,"eighty":-0.832971,"marketCap":18169013},{"date":"2024-08-23","current":-0.438223,"twenty":-7.173788,"median":-1.810124,"eighty":-0.819084,"marketCap":18891808},{"date":"2024-08-30","current":-0.445026,"twenty":-7.134289,"median":-1.807043,"eighty":-0.782201,"marketCap":19185057},{"date":"2024-09-06","current":-0.439756,"twenty":-7.101601,"median":-1.801705,"eighty":-0.770493,"marketCap":18957892},{"date":"2024-09-13","current":-0.438511,"twenty":-7.072999,"median":-1.793286,"eighty":-0.755312,"marketCap":18904199},{"date":"2024-09-20","current":-0.432762,"twenty":-7.018518,"median":-1.790211,"eighty":-0.727289,"marketCap":18656383},{"date":"2024-09-27","current":-0.419541,"twenty":-6.940882,"median":-1.784867,"eighty":-0.723579,"marketCap":18086408},{"date":"2024-10-04","current":-0.421553,"twenty":-6.859161,"median":-1.781604,"eighty":-0.720299,"marketCap":18173143},{"date":"2024-10-11","current":-0.418774,"twenty":-6.793784,"median":-1.770512,"eighty":-0.713971,"marketCap":18053366},{"date":"2024-10-18","current":-0.488618,"twenty":-6.761095,"median":-1.759609,"eighty":-0.708159,"marketCap":21064325},{"date":"2024-10-25","current":-0.560474,"twenty":-6.743388,"median":-1.745401,"eighty":-0.702865,"marketCap":24162020},{"date":"2024-10-31","current":-0.540929,"twenty":-6.727044,"median":-1.742067,"eighty":-0.692281,"marketCap":23319447},{"date":"2024-11-08","current":-0.524833,"twenty":-6.682097,"median":-1.737965,"eighty":-0.681909,"marketCap":22625563},{"date":"2024-11-15","current":-0.545785,"twenty":-6.620806,"median":-1.716758,"eighty":-0.674911,"marketCap":21518654},{"date":"2024-11-22","current":-0.514358,"twenty":-6.558153,"median":-1.699284,"eighty":-0.661508,"marketCap":20279576},{"date":"2024-11-29","current":-0.572603,"twenty":-6.503672,"median":-1.688964,"eighty":-0.65569,"marketCap":22576000},{"date":"2024-12-06","current":-0.518548,"twenty":-6.476431,"median":-1.667043,"eighty":-0.649336,"marketCap":20444786},{"date":"2024-12-13","current":-0.405515,"twenty":-6.476431,"median":-1.652502,"eighty":-0.643925,"marketCap":15988236},{"date":"2024-12-20","current":-0.400277,"twenty":-6.360659,"median":-1.630914,"eighty":-0.638717,"marketCap":15781723},{"date":"2024-12-27","current":-0.45077,"twenty":-6.289833,"median":-1.611709,"eighty":-0.636941,"marketCap":17772508},{"date":"2025-01-03","current":-0.439351,"twenty":-6.153631,"median":-1.593134,"eighty":-0.634884,"marketCap":17322310},{"date":"2025-01-10","current":-0.398077,"twenty":-6.028325,"median":-1.567109,"eighty":-0.629734,"marketCap":15694987},{"date":"2025-01-17","current":-0.40122,"twenty":-5.912553,"median":-1.556809,"eighty":-0.62477,"marketCap":15818895},{"date":"2025-01-24","current":-0.401534,"twenty":-5.828107,"median":-1.545109,"eighty":-0.618263,"marketCap":15831286},{"date":"2025-01-31","current":-0.383516,"twenty":-5.768178,"median":-1.51435,"eighty":-0.616204,"marketCap":15120881},{"date":"2025-02-07","current":-0.424685,"twenty":-5.716421,"median":-1.486502,"eighty":-0.612716,"marketCap":16744073},{"date":"2025-02-14","current":-0.429714,"twenty":-5.391371,"median":-1.471205,"eighty":-0.608371,"marketCap":16942326},{"date":"2025-02-21","current":-0.445323,"twenty":-4.919282,"median":-1.46057,"eighty":-0.606587,"marketCap":17557734},{"date":"2025-02-28","current":-0.400068,"twenty":-4.842511,"median":-1.459862,"eighty":-0.602187,"marketCap":15773462},{"date":"2025-03-07","current":-0.376497,"twenty":-4.836605,"median":-1.452758,"eighty":-0.601434,"marketCap":14844154},{"date":"2025-03-14","current":-0.345594,"twenty":-4.783456,"median":-1.449206,"eighty":-0.596732,"marketCap":13625727},{"date":"2025-03-21","current":-0.351984,"twenty":-4.71259,"median":-1.441679,"eighty":-0.594286,"marketCap":13877673},{"date":"2025-03-28","current":-0.332604,"twenty":-4.71259,"median":-1.437925,"eighty":-0.591404,"marketCap":13113575},{"date":"2025-04-04","current":-0.306624,"twenty":-4.683062,"median":-1.413596,"eighty":-0.586076,"marketCap":12089270},{"date":"2025-04-11","current":-0.309138,"twenty":-4.671251,"median":-1.409015,"eighty":-0.585549,"marketCap":12188396},{"date":"2025-04-17","current":-0.097942,"twenty":-4.666527,"median":-1.403958,"eighty":-0.580748,"marketCap":5194448},{"date":"2025-04-25","current":-0.111399,"twenty":-4.660621,"median":-1.395354,"eighty":-0.5753,"marketCap":5908156},{"date":"2025-04-28","current":-0.103357,"twenty":-4.65944,"median":-1.394781,"eighty":-0.574822,"marketCap":5481620},{"date":"2025-09-19","current":-0.103464,"twenty":-4.640542,"median":-1.390598,"eighty":-0.572603,"marketCap":5001220},{"date":"2025-09-26","current":-0.090272,"twenty":-4.631094,"median":-1.375829,"eighty":-0.568634,"marketCap":4363575},{"date":"2025-10-03","current":-0.100173,"twenty":-4.625188,"median":-1.369421,"eighty":-0.563703,"marketCap":4842161},{"date":"2025-10-10","current":-2.042014,"twenty":-4.543693,"median":-1.369421,"eighty":-0.563621,"marketCap":98706893},{"date":"2025-10-17","current":-1.825651,"twenty":-4.484119,"median":-1.369421,"eighty":-0.563621,"marketCap":88248325},{"date":"2025-10-24","current":-1.514518,"twenty":-4.443681,"median":-1.369421,"eighty":-0.563621,"marketCap":73208750},{"date":"2025-10-31","current":-1.250246,"twenty":-4.397236,"median":-1.367716,"eighty":-0.563621,"marketCap":60434409},{"date":"2025-11-07","current":-1.3906,"twenty":-4.275563,"median":-1.363958,"eighty":-0.563621,"marketCap":67218841},{"date":"2025-11-14","current":-1.324843,"twenty":-4.227486,"median":-1.347974,"eighty":-0.563621,"marketCap":63432181},{"date":"2025-11-21","current":-2.293921,"twenty":-4.101491,"median":-1.347974,"eighty":-0.563621,"marketCap":109830665},{"date":"2025-11-28","current":-2.235573,"twenty":-3.839757,"median":-1.347974,"eighty":-0.563621,"marketCap":107037000},{"date":"2025-12-05","current":-2.021852,"twenty":-3.651983,"median":-1.347974,"eighty":-0.563621,"marketCap":96804262},{"date":"2025-12-12","current":-1.97647,"twenty":-3.51742,"median":-1.347974,"eighty":-0.563621,"marketCap":94631411},{"date":"2025-12-19","current":-1.716249,"twenty":-3.295969,"median":-1.347974,"eighty":-0.563621,"marketCap":82172304},{"date":"2025-12-26","current":-1.877881,"twenty":-3.05905,"median":-1.347974,"eighty":-0.563621,"marketCap":89911080},{"date":"2026-01-02","current":-1.947408,"twenty":-2.955924,"median":-1.347974,"eighty":-0.563621,"marketCap":93239930},{"date":"2026-01-09","current":-1.647617,"twenty":-2.850694,"median":-1.347974,"eighty":-0.563621,"marketCap":78886269},{"date":"2026-01-16","current":-1.674221,"twenty":-2.815743,"median":-1.347974,"eighty":-0.563621,"marketCap":80160009},{"date":"2026-01-23","current":-1.905602,"twenty":-2.76968,"median":-1.347974,"eighty":-0.563621,"marketCap":91238338},{"date":"2026-01-30","current":-1.785329,"twenty":-2.685822,"median":-1.347974,"eighty":-0.563621,"marketCap":85479748},{"date":"2026-02-06","current":-1.583903,"twenty":-2.650389,"median":-1.347974,"eighty":-0.563621,"marketCap":75835714},{"date":"2026-02-13","current":-1.854631,"twenty":-2.594878,"median":-1.347974,"eighty":-0.563621,"marketCap":88797895},{"date":"2026-02-20","current":-1.176359,"twenty":-2.527535,"median":-1.341686,"eighty":-0.563621,"marketCap":56322869},{"date":"2026-02-27","current":-1.308928,"twenty":-2.431061,"median":-1.324843,"eighty":-0.563621,"marketCap":62670163},{"date":"2026-03-06","current":-1.202291,"twenty":-2.386495,"median":-1.31338,"eighty":-0.563621,"marketCap":57564498},{"date":"2026-03-13","current":-2.109156,"twenty":-2.345429,"median":-1.312952,"eighty":-0.563621,"marketCap":82185375},{"date":"2026-03-20","current":-2.07905,"twenty":-2.292556,"median":-1.312952,"eighty":-0.563621,"marketCap":81012278},{"date":"2026-03-27","current":-2.433452,"twenty":-2.263858,"median":-1.312952,"eighty":-0.563621,"marketCap":94821891},{"date":"2026-04-02","current":-2.448241,"twenty":-2.255003,"median":-1.312952,"eighty":-0.563621,"marketCap":95398149},{"date":"2026-04-10","current":-2.324297,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":90568558},{"date":"2026-04-17","current":-2.391256,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":93177676},{"date":"2026-04-24","current":-3.745574,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":145950034},{"date":"2026-05-01","current":-3.975121,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":154894574},{"date":"2026-05-08","current":-3.923109,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":152867866},{"date":"2026-05-15","current":-4.286908,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":159434402},{"date":"2026-05-22","current":-3.829154,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":142410050},{"date":"2026-05-29","current":-3.574119,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":132925054},{"date":"2026-06-05","current":-3.863304,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":143680121},{"date":"2026-06-12","current":-3.63396,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":135150611},{"date":"2026-06-18","current":-3.608429,"twenty":-2.234417,"median":-1.312952,"eighty":-0.563621,"marketCap":134201075},{"date":"2026-06-26","current":-3.905184,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":145237710},{"date":"2026-07-02","current":-3.888533,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":144618447},{"date":"2026-07-10","current":-3.82896,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":142402863},{"date":"2026-07-17","current":-3.276891,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":121870869},{"date":"2026-07-24","current":-3.329434,"twenty":-2.229792,"median":-1.311815,"eighty":-0.563593,"marketCap":123824987},{"date":"2026-07-31","current":-3.209548,"twenty":-2.221734,"median":-1.310679,"eighty":-0.563384,"marketCap":119366296},{"date":"2026-08-07","current":-3.43526,"twenty":-2.221734,"median":-1.310679,"eighty":-0.563384,"marketCap":127760744},{"date":"2026-08-14","current":-2.785419,"twenty":-2.221734,"median":-1.310679,"eighty":-0.563384,"marketCap":143039627},{"date":"2026-08-21","current":-2.909383,"twenty":-2.221734,"median":-1.310679,"eighty":-0.563384,"marketCap":149405565}],"updateTime":1787586345626},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"SPRB\",pageSize:20,pageCount:5,lang_content:\"en\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2618352049","title":"Spruce Biosciences price target lowered to $170 from $180 at Citizens","url":"https://stock-news.laohu8.com/highlight/detail?id=2618352049","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618352049?lang=en_us&edition=fundamental","pubTime":"2026-03-10 17:40","pubTimestamp":1773135619,"startTime":"0","endTime":"0","summary":"Citizens lowered the firm’s price target on Spruce Biosciences (SPRB) to $170 from $180 and keeps an Outperform rating on the shares. The firm cont...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spruce-biosciences-price-target-lowered-to-170-from-180-at-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spruce-biosciences-price-target-lowered-to-170-from-180-at-citizens-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SPRB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618832623","title":"Rpt-Spruce Biosciences FY Net Income USD -38.966 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2618832623","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618832623?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:36","pubTimestamp":1773056201,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nFWN3ZX10G:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SPRB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618628762","title":"Spruce Biosciences Inc - to Offer and Sell Common Stock up to $75 Mln Through Jefferies - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2618628762","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618628762?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:32","pubTimestamp":1773055976,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nFWN3ZX0UY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618993628","title":"Spruce Biosciences Inc - May Offer and Sell Common Stock up to Maximum Program Amount Under Sales Agreement - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2618993628","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618993628?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:24","pubTimestamp":1773055479,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nFWN3ZX10F:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SPRB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618628994","title":"Spruce Biosciences Inc - Enters Open Market Sale Agreement With Jefferies Llc on March 9, 2026 - SEC Filing","url":"https://stock-news.laohu8.com/highlight/detail?id=2618628994","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618628994?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:24","pubTimestamp":1773055479,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nFWN3ZX10F:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618289256","title":"BRIEF-Spruce Biosciences Reports Full Year 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2618289256","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618289256?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:24","pubTimestamp":1773055469,"startTime":"0","endTime":"0","summary":"BRIEF-Spruce Biosciences Reports Full Year 2025 Financial ResultsMarch 9 (Reuters) - Spruce Biosciences SPRB.O:SPRUCE BIOSCIENCES FY NET INCOME USD -38.966 MILLIONSPRUCE BIOSCIENCES FY INCOME FROM OPE","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nPLX579C05:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618288436","title":"Spruce Biosciences 2025 net loss narrows, secures $50 mln funding","url":"https://stock-news.laohu8.com/highlight/detail?id=2618288436","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618288436?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:14","pubTimestamp":1773054873,"startTime":"0","endTime":"0","summary":"Spruce Biosciences 2025 net loss narrows, secures $50 mln fundingOverviewBiopharmaceutical firm's net loss for 2025 decreased compared to 2024Company secured up to $50 mln in growth capital from Avenu","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nL1N3ZX0EY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4080","SPRB","BK4231","BK4139","BRX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618664076","title":"Spruce Biosciences FY 2025 R&D expenses fall 58% to USD 19.52 million, net loss narrows 27% to USD 38.97 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2618664076","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618664076?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:05","pubTimestamp":1773054325,"startTime":"0","endTime":"0","summary":"Spruce Biosciences reported a FY 2025 net loss of USD 38.97 million, narrowing 27%. R&D expenses fell 58% to USD 19.52 million, while G&A expenses rose 16% to USD 16.99 million. Total operating expenses decreased 40% to USD 36.51 million. Cash and cash equivalents were USD 48.91 million at year-end, and the company said it expects its cash to fund its current operating plan into early 2027. Spruce said it plans to submit a BLA for tralesinidase alfa  in MPS IIIB in Q4 2026 and cited positive Type B meeting feedback from the FDA supporting a potential accelerated approval pathway based on a surrogate endpoint.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nNDLcfkyWl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618640021","title":"Spruce Biosciences Inc - Expects Cash and Cash Equivalents to Fund Current Operating Plan Into Early 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2618640021","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618640021?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:05","pubTimestamp":1773054300,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nTUABQK9RF:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618020640","title":"Spruce Biosciences Inc - Bla Submission for Ta-Ert for Treatment of Sanfilippo Syndrome Type B (Mps Iiib) on Track for Q4 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2618020640","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618020640?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:05","pubTimestamp":1773054300,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nTUABQK9RF:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618823623","title":"Spruce Biosciences Inc - Net Loss $39.0 Mln for Year Ended Dec 31, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2618823623","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618823623?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:05","pubTimestamp":1773054300,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nPLX579C05:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618064076","title":"Press Release: Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates","url":"https://stock-news.laohu8.com/highlight/detail?id=2618064076","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618064076?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:05","pubTimestamp":1773054300,"startTime":"0","endTime":"0","summary":"Following Positive Type B Meetings with the FDA, BLA Submission for TA-ERT for the Treatment of Sanfilippo Syndrome Type B  on Track for the Fourth Quarter of 2026. Appoints Dale Hooks as Chief Commercial Officer, Strengthening the Company's Commercial Capabilities in Preparation for a Potential Launch of TA-ERT. Secured up to $50 Million in Growth Capital from Avenue Capital Group. Spruce Biosciences, Inc. , a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need, today reported financial results for the year ended December 31, 2025 and provided corporate updates.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0211328371.USD","BK4555","PA3.SI","LU0052756011.USD","BK4604","CAH","LU1571399168.USD","LU0310800965.SGD","03160","LU0006061336.USD","BK4588","LU1880398554.USD","TM","LU0162691827.USD","LU0154236417.USD","LU0310799852.SGD","LU0889566641.SGD","BK6512","BK4175","LU1880398471.USD","LABU","LU0072461881.USD","LU1267930490.SGD","SPRB","BK4139","BK4099","LU0792757196.USD","LU0211327993.USD","LU1267930813.SGD","LU1267930227.SGD","LU0128525689.USD","SG9999001440.SGD","BK4585","BK6045"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618640900","title":"Spruce Biosciences names Dale Hooks chief commercial officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2618640900","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618640900?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:00","pubTimestamp":1773054042,"startTime":"0","endTime":"0","summary":"Spruce Biosciences appointed Dale Hooks as chief commercial officer. Hooks previously served as chief commercial officer at Applied Therapeutics and held senior commercial roles at Reata Pharmaceuticals and Clovis Oncology. He also held commercial leadership positions at Genentech, Galderma, Novartis, and Glaxo Wellcome.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news brief via Business Wire  on March 09, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nNDL2c4tHw:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0889565916.HKD","LU1670756490.USD","SPRB","BK4532","BK4585","GSK.UK","LU1400636491.USD","LU0109981661.USD","LU0321505868.SGD","IE00B19Z9P08.USD","LU1302929846.USD","LU1645745479.HKD","IE0034235071.USD","LU0234570918.USD","BIIB","LU1309081286.SGD","LU1481599808.USD","LU0161305163.EUR","LU1046248800.SGD","LU1202635105.USD","LU0971552830.HKD","LU1983299246.USD","IE00B19Z9Z06.USD","LU0203345920.USD","LU0321505439.SGD","LU1400636574.HKD","LU1098665638.USD","LU0289739699.SGD","LU0203347892.USD","LU1015430645.USD","LU0545562505.USD","LU1228905037.USD","IE00B3T34201.USD","LU0225284248.USD","LU0320765992.SGD","LU0211331839.USD","LU0575583348.USD","LU0306807586.USD","IE00B894F039.SGD","LU1035777561.USD","LU0985481810.HKD","BK4588","BK4139","LU1064927863.SGD","LU0971552673.USD","LU1228905540.USD","IE00BWDBJ516.SGD","BK4533","LU0058720904.USD","LU0109394709.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618064093","title":"Spruce Biosciences Appoints Dale Hooks, an Accomplished Rare Disease Commercial Leader, as Chief Commercial Officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2618064093","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618064093?lang=en_us&edition=fundamental","pubTime":"2026-03-09 19:00","pubTimestamp":1773054004,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nTUA5S9C6F:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616171366","title":"Spruce Biosciences CEO Javier Szwarcberg to Present at Leerink Global Healthcare Conference and The Citizens Life Sciences Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2616171366","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616171366?lang=en_us&edition=fundamental","pubTime":"2026-03-03 05:05","pubTimestamp":1772485520,"startTime":"0","endTime":"0","summary":"Spruce Biosciences CEO Javier Szwarcberg to Present at Leerink Global Healthcare Conference and The Citizens Life Sciences Conference","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260302:nNDL13t8r:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":5,"pageCount":5,"totalSize":95,"code":"91000000","status":"200"}]}}