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Ultragenyx Pharmaceutical

25.72

-0.1100-0.43%

Post-market: 25.720.00000.00%16:20 EDT

Volume:1.53M

Turnover:39.47M

Market Cap:2.53B

PE:-4.41

High:26.09

Open:25.75

Low:25.30

Close:25.83

52wk High:39.89

52wk Low:18.29

Shares:98.32M

Float Shares:94.49M

Volume Ratio:0.63

T/O Rate:1.62%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-5.8279

EPS(LYR):-5.8316

ROE:-608.47%

ROA:-24.22%

PB:-8.69

PE(LYR):-4.41

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Overview Company News Filings

Ultragenyx's Gene Therapy Study Shows Ammonia Reduction In Rare Metabolic Disorder

Benzinga_recent_news

Ultragenyx's gene therapy helps control ammonia levels in late-stage study

Ultragenyx Phase 3 Enh3ance study showed statistically significant results

Ultragenyx reports Phase 3 Enh3ance trial shows DTX301 cuts plasma ammonia AUC by 18% at Week 36

Ultragenyx Announces Positive 36-Week Data From Phase 3 Study of Dtx301 Aav8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (Otc) Deficiency

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Dtx301 Shows 18% Reduction in 24-Hour Plasma Ammonia at Week 36 Versus Placebo

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Dtx301 Well Tolerated With Acceptable Safety Profile

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Fewer Hyperammonemic Crises and No Deaths in Dtx301 Group Compared to Placebo

THOMSON REUTERS

Ultragenyx Pharmaceutical Inc - Secondary Endpoint Data on Treatment Burden Reduction Expected First Half 2027

THOMSON REUTERS

Ultragenyx Announces Positive 36-Week Data from Phase 3 Study of DTX301 AAV8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (OTC) Deficiency

Ultragenyx price target lowered to $74 from $120 at JPMorgan

Ultragenyx faces securities class action over August 2023–December 2025 disclosures

How Setrusumab Trial Setbacks and Securities Suits May Impact Ultragenyx Pharmaceutical (RARE) Investors

Simply Wall St.

Ultragenyx Faces Securities Class Action Over Setrusumab Trial Disclosures

Samhi Hotels to Acquire 70% Stake in Luxury Hotel Aggregator RARE India

Rosen Law Firm Urges Ultragenyx Investors to Seek Counsel Ahead of April 6 Lead Plaintiff Deadline

Levi & Korsinsky Files Securities Class Action Against Ultragenyx

Ultragenyx Hit With Securities Class Action Lawsuit

Class Action Lawsuit Targets Ultragenyx Pharmaceutical Inc. Investors

Ultragenyx Investors File Securities Class Action Lawsuit

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ammonia AUC by 18% at Week 36","url":"https://stock-news.laohu8.com/highlight/detail?id=2618134272","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618134272?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:33","pubTimestamp":1773318800,"startTime":"0","endTime":"0","summary":"Ultragenyx reported positive 36-week results from the Phase 3 Enh3ance trial of DTX301, an investigational AAV8 gene therapy for ornithine transcarbamylase deficiency. In the randomized, double-blind, placebo-controlled period, DTX301  reduced 24-hour plasma ammonia AUC0-24 by 18% versus placebo  at Week 36 . The company also reported a mean 27% reduction in ammonia scavenger medications at Week 36 among treated patients. The study is continuing to a second primary endpoint evaluating treatment burden through 64 weeks of follow-up, with data expected in the first half of 2027.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nNDL3swplM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LU2210149790.SGD","LU0314104364.USD","LU2210150020.SGD","IE00B64PRP62.GBP","IE00BKPKM429.USD","RARE","BK4112","BK4139","SG9999014005.SGD","SG9999014013.SGD","NDAQ","IE00B3QW5Z07.USD","SG9999014039.USD","BK4588","IE00BGHQF748.EUR","LU2095319765.USD","SG9999014021.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618713448","title":"Ultragenyx Announces Positive 36-Week Data From Phase 3 Study of Dtx301 Aav8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (Otc) Deficiency","url":"https://stock-news.laohu8.com/highlight/detail?id=2618713448","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618713448?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618424134","title":"Ultragenyx Pharmaceutical Inc - Dtx301 Shows 18% Reduction in 24-Hour Plasma Ammonia at Week 36 Versus Placebo","url":"https://stock-news.laohu8.com/highlight/detail?id=2618424134","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618424134?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618213443","title":"Ultragenyx Pharmaceutical Inc - Dtx301 Well Tolerated With Acceptable Safety Profile","url":"https://stock-news.laohu8.com/highlight/detail?id=2618213443","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618213443?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618134426","title":"Ultragenyx Pharmaceutical Inc - Fewer Hyperammonemic Crises and No Deaths in Dtx301 Group Compared to Placebo","url":"https://stock-news.laohu8.com/highlight/detail?id=2618134426","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618134426?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618134425","title":"Ultragenyx Pharmaceutical Inc - Secondary Endpoint Data on Treatment Burden Reduction Expected First Half 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2618134425","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618134425?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318603,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260312:nTUAGM4TB:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618460132","title":"Ultragenyx Announces Positive 36-Week Data from Phase 3 Study of DTX301 AAV8 Gene Therapy for the Treatment of Ornithine Transcarbamylase (OTC) Deficiency","url":"https://stock-news.laohu8.com/highlight/detail?id=2618460132","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618460132?lang=en_us&edition=fundamental","pubTime":"2026-03-12 20:30","pubTimestamp":1773318600,"startTime":"0","endTime":"0","summary":"Statistically significant improvements in primary endpoint of ammonia control compared with placebo at 36 weeks Clinically important changes observed in patient global impression scale for overall OTC","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/03/12/3254660/20739/en/Ultragenyx-Announces-Positive-36-Week-Data-from-Phase-3-Study-of-DTX301-AAV8-Gene-Therapy-for-the-Treatment-of-Ornithine-Transcarbamylase-OTC-Deficiency.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618136393","title":"Ultragenyx price target lowered to $74 from $120 at JPMorgan","url":"https://stock-news.laohu8.com/highlight/detail?id=2618136393","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618136393?lang=en_us&edition=fundamental","pubTime":"2026-03-12 18:54","pubTimestamp":1773312883,"startTime":"0","endTime":"0","summary":"JPMorgan lowered the firm’s price target on Ultragenyx (RARE) to $74 from $120 and keeps an Overweight rating on the shares. At current share level...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-74-from-120-at-jpmorgan-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-price-target-lowered-to-74-from-120-at-jpmorgan-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IE000M9KFDE8.USD","LU1145028129.USD","IE00BJLML261.HKD","LU0345770308.USD","LU0211327993.USD","BK4516","BK4588","IE00BWXC8680.SGD","LU0211326755.USD","LU0820561818.USD","LU1894683348.USD","LU0211326839.USD","LU1720051017.SGD","LU2237443895.HKD","LU0170899867.USD","LU0238689110.USD","LU1720051108.HKD","JPMO","LU2746668974.SGD","LU0868494708.USD","LU2430703178.SGD","LU2264538146.SGD","LU2756315664.SGD","LU0820561909.HKD","LU0417517546.SGD","RARE","IE00B3S45H60.SGD","LU0345770993.USD","LU0971096721.USD","LU0211331839.USD","LU0496365809.HKD","LU0265550946.USD","LU1244550494.USD","LU2211815571.USD","IE00BKVL7J92.USD","LU1496350171.SGD","LU2023250504.SGD","LU2023250843.SGD","LU0345769128.USD","LU0208291251.USD","LU0267386448.USD","LU0787776722.HKD","IE00BYXW3230.USD","LU2357305700.SGD","LU0048584097.USD","LU0683600562.USD","LU1064131342.USD","LU0964807845.USD","IE00BJTD4N35.SGD","LU2505996509.AUD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618403199","title":"Ultragenyx faces securities class action over August 2023–December 2025 disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2618403199","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618403199?lang=en_us&edition=fundamental","pubTime":"2026-03-11 21:02","pubTimestamp":1773234138,"startTime":"0","endTime":"0","summary":"Ultragenyx is facing a pending securities class action covering the period from Aug. 3, 2023 to Dec. 26, 2025. Investors seeking to serve as lead plaintiff must file by April 6, 2026. The suit names Ultragenyx CEO Emil Kakkis and CMO Eric Crombez as individual defendants under Section 20 control-person claims. The complaint alleges they had authority over SEC filings and other public statements, and that they had access to non-public information related to study progress and risks.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260311:nNDL4bGSJ8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2618959236","title":"How Setrusumab Trial Setbacks and Securities Suits May Impact Ultragenyx Pharmaceutical (RARE) Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2618959236","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618959236?lang=en_us&edition=fundamental","pubTime":"2026-03-10 21:21","pubTimestamp":1773148903,"startTime":"0","endTime":"0","summary":"In past months, several law firms announced securities class actions against Ultragenyx Pharmaceutical, alleging the company misled investors about the reliability and risks of Phase III Orbit and Cosmic trials for setrusumab in osteogenesis imperfecta, after the studies failed to reach statistical significance. \nThe litigation raises questions about Ultragenyx’s clinical disclosure practices and could influence how investors view the company’s risk profile, capital allocation, and future...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rare/ultragenyx-pharmaceutical/news/how-setrusumab-trial-setbacks-and-securities-suits-may-impac","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rare/ultragenyx-pharmaceutical/news/how-setrusumab-trial-setbacks-and-securities-suits-may-impac","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["AIYY","BK4551","ISBC","RARE","AI","BK4528","BK4585","BK4543","BK4588","BK4139","BK4023","BK4211","BK4587"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617502663","title":"Ultragenyx Faces Securities Class Action Over Setrusumab Trial Disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2617502663","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617502663?lang=en_us&edition=fundamental","pubTime":"2026-03-08 03:05","pubTimestamp":1772910316,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical Inc. is facing a proposed securities class action in the U.S. District Court for the Northern District of California on behalf of investors who bought shares between Aug. 3, 2023 and Dec. 26, 2025. The suit alleges the company and certain executives made misleading statements and omissions about the prospects and interim benchmarks for setrusumab in Phase III Osteogenesis Imperfecta studies, before later disclosures that the Orbit and Cosmic trials failed to meet primary endpoints. Investors seeking to be appointed lead plaintiff have until April 6, 2026.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260307:nNDL4Vz2jS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3QW5Z07.USD","IE00B64PRP62.GBP","IE00BGHQF748.EUR","NDAQ","LU2210150020.SGD","BK4112","BK4585","LU2095319765.USD","SG9999014013.SGD","IE00BKPKM429.USD","RARE","BK4588","SG9999014021.USD","LU2210149790.SGD","LU0314104364.USD","SG9999014039.USD","SG9999014005.SGD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617526103","title":"Samhi Hotels to Acquire 70% Stake in Luxury Hotel Aggregator RARE India","url":"https://stock-news.laohu8.com/highlight/detail?id=2617526103","media":"TIPRANKS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617526103?lang=en_us&edition=fundamental","pubTime":"2026-03-05 22:54","pubTimestamp":1772722455,"startTime":"0","endTime":"0","summary":"Samhi Hotels Limited ( ($IN:SAMHI) ) has issued an update. Samhi Hotels’ board has approved investing INR 473.9 million to acquire a 70% partnershi...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/samhi-hotels-to-acquire-70-stake-in-luxury-hotel-aggregator-rare-india?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/samhi-hotels-to-acquire-70-stake-in-luxury-hotel-aggregator-rare-india?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE","MNDmain","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617998715","title":"Rosen Law Firm Urges Ultragenyx Investors to Seek Counsel Ahead of April 6 Lead Plaintiff Deadline","url":"https://stock-news.laohu8.com/highlight/detail?id=2617998715","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617998715?lang=en_us&edition=fundamental","pubTime":"2026-03-05 10:41","pubTimestamp":1772678477,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against Ultragenyx Pharmaceutical Inc. on behalf of investors who bought its common stock between Aug. 3, 2023 and Dec. 26, 2025. The suit alleges the company made materially false or misleading statements about the expected Phase III results for setrusumab in osteogenesis imperfecta, including claims about reducing annualized fracture rates, and that the truth later caused investor losses. An April 6, 2026 deadline has been set for motions to be appointed lead plaintiff.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260305:nNDL87LgT2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616555722","title":"Levi & Korsinsky Files Securities Class Action Against Ultragenyx","url":"https://stock-news.laohu8.com/highlight/detail?id=2616555722","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616555722?lang=en_us&edition=fundamental","pubTime":"2026-03-04 22:01","pubTimestamp":1772632900,"startTime":"0","endTime":"0","summary":"Levi and Korsinsky has reminded investors of a pending securities class action involving Ultragenyx Pharmaceutical Inc., seeking damages for purchasers of the company’s securities between Aug. 3, 2023 and Dec. 26, 2025. The suit centers on alleged misrepresentations about the efficacy potential of setrusumab, after Ultragenyx disclosed that its Phase III Orbit and Cosmic studies failed to meet primary endpoints on reduced annualized fracture rates, a development that preceded a sharp decline in the company’s share price. Investors have until April 6, 2026 to seek lead plaintiff status.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260304:nNDLbKRsqL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616665453","title":"Ultragenyx Hit With Securities Class Action Lawsuit","url":"https://stock-news.laohu8.com/highlight/detail?id=2616665453","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616665453?lang=en_us&edition=fundamental","pubTime":"2026-03-03 05:00","pubTimestamp":1772485242,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against Ultragenyx Pharmaceutical Inc. in the U.S. District Court for the Northern District of California, alleging violations of Section 10 of the Securities Exchange Act and SEC Rule 10b-5 tied to purportedly false and misleading statements about Phase III clinical studies. The suit covers investors who bought shares between Aug. 3, 2023 and Dec. 26, 2025, and also asserts control-person claims under Section 20. Motions for lead plaintiff are due by April 6, 2026.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260302:nNDL2JlgyG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","SG9999014039.USD","IE00BGHQF748.EUR","IE00BKPKM429.USD","NDAQ","IE00B64PRP62.GBP","LU0314104364.USD","RARE","LU2095319765.USD","LU2210149790.SGD","BK4139","BK4112","SG9999014013.SGD","SG9999014021.USD","SG9999014005.SGD","BK4585","IE00B3QW5Z07.USD","LU2210150020.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616735598","title":"Class Action Lawsuit Targets Ultragenyx Pharmaceutical Inc. Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2616735598","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616735598?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:00","pubTimestamp":1772384417,"startTime":"0","endTime":"0","summary":"A securities class action lawsuit has been filed against Ultragenyx Pharmaceutical Inc. and certain officers, seeking damages for alleged federal securities law violations. The suit covers investors who purchased or acquired Ultragenyx securities between Aug. 3, 2023 and Dec. 26, 2025, and alleges the company made false or misleading statements and omissions about the Phase III Orbit study of setrusumab for osteogenesis imperfecta, including risks around interim analysis benchmarks and reliance on Phase II results without a placebo control. Investors who suffered losses have until April 6, 2026 to seek appointment as lead plaintiff.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nNDLbydbsm:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","BK4112","LU2210150020.SGD","SG9999014005.SGD","SG9999014013.SGD","IE00BKPKM429.USD","LU0314104364.USD","SG9999014021.USD","IE00B3QW5Z07.USD","LU2095319765.USD","BK4139","RARE","NDAQ","IE00BGHQF748.EUR","BK4588","LU2210149790.SGD","SG9999014039.USD","IE00B64PRP62.GBP"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2614864069","title":"Ultragenyx Investors File Securities Class Action Lawsuit","url":"https://stock-news.laohu8.com/highlight/detail?id=2614864069","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614864069?lang=en_us&edition=fundamental","pubTime":"2026-02-26 09:21","pubTimestamp":1772068866,"startTime":"0","endTime":"0","summary":"Investors who bought or acquired Ultragenyx Pharmaceutical Inc. shares between Aug. 3, 2023 and Dec. 26, 2025 face a proposed securities class action in U.S. federal court alleging the company and certain executives made misleading statements about the Phase III Orbit study of setrusumab for osteogenesis imperfecta. The suit points to disclosures in July 2025 and December 2025 that the Orbit and Cosmic studies did not meet key statistical endpoints, followed by sharp stock declines, and sets an April 6, 2026 deadline for investors to seek lead-plaintiff status.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260226:nNDL6Prgxj:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":7,"pageCount":7,"totalSize":140,"code":"91000000","status":"200"}]}}