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Ultragenyx Pharmaceutical

15.29

+0.40002.69%

Pre-market: 15.28-0.0100-0.07%05:52 EDT

Volume:5.40M

Turnover:81.85M

Market Cap:1.50B

PE:-2.62

High:15.52

Open:14.79

Low:14.43

Close:14.89

52wk High:39.89

52wk Low:12.73

Shares:98.32M

Float Shares:80.72M

Volume Ratio:1.30

T/O Rate:6.69%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-5.8279

EPS(LYR):-5.8316

ROE:-608.47%

ROA:-24.22%

PB:-5.17

PE(LYR):-2.62

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Overview Company News Filings

Ultragenyx downgraded to In Line from Outperform at Evercore ISI

Evercore ISI downgrades Ultragenyx Pharmaceutical (RARE) to a Hold

Ultragenyx downgraded to Market Perform from Outperform at William Blair

William Blair downgrades Ultragenyx Pharmaceutical (RARE) to a Hold

Ultragenyx Says Phase 3 Study on Rare Neurogenetic Disorder Missed Primary, Secondary Endpoints; Shares Fall After-Hours

MT Newswires Live

Ultragenyx Pharmaceutical to Cut Costs After Drug Trial Misses Endpoints

Ultragenyx's Rare Disease Drug Fails in Late-Stage Trial

Ultragenyx Announces Phase 3 Aspire Results in Angelman Syndrome

THOMSON REUTERS

Ultragenyx Pharmaceutical - Safety Profile in Aspire Study Consistent with Phase 1/2

THOMSON REUTERS

Ultragenyx Pharmaceutical - to Evaluate Apazunersen Program and Implement Significant Expense Reductions

THOMSON REUTERS

Ultragenyx Pharmaceutical - Expects to Continue Toward Profitability in 2027

THOMSON REUTERS

Ultragenyx Announces Phase 3 Aspire results in Angelman Syndrome

Ultragenyx Unit Amlogenyx Presents at Wells Fargo Healthcare Conference Sept. 8

Ultragenyx announces publication of Phase 3 Genglycos trial results

Ultragenyx Announces the Publication of a Successful 96-Week Randomized, Placebo-Controlled Trial with Crossover Treatment of Genglycos™ (Also Known as Dtx401) Aav Gene Therapy in Gsdia in the Journal of Inherited Metabolic Disease

THOMSON REUTERS

Ultragenyx Grants 45,984 Inducement RSUs to 23 New Hires

Ultragenyx Reports Inducement Grant Under NASDAQ Listing Rule 5635(c)(4)

THOMSON REUTERS

Ultragenyx Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

Ultragenyx Pharma Price Target Raised to $80.00/Share from $75.00 by JP Morgan

Ultragenyx Pharmaceutical Inc. : Morgan Stanley Raises Target Price to $74 from $67

THOMSON REUTERS

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The firm notes that it is disappointed the Phase 3 Angelman syndrome ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-market-perform-from-outperform-at-william-blair-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ultragenyx-downgraded-to-market-perform-from-outperform-at-william-blair-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664449248","title":"William Blair downgrades Ultragenyx Pharmaceutical (RARE) to a Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2664449248","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664449248?lang=en_us&edition=fundamental","pubTime":"2026-09-03 06:05","pubTimestamp":1788386726,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical received a Hold rating and price target from William Blair analyst Sami Corwin today. According to TipRanks, Corwin is a ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/william-blair-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/william-blair-downgrades-ultragenyx-pharmaceutical-rare-to-a-hold-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664841022","title":"Ultragenyx Says Phase 3 Study on Rare Neurogenetic Disorder Missed Primary, Secondary Endpoints; Shares Fall After-Hours","url":"https://stock-news.laohu8.com/highlight/detail?id=2664841022","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664841022?lang=en_us&edition=fundamental","pubTime":"2026-09-03 05:20","pubTimestamp":1788384025,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical  said late Wednesday the phase 3 Aspire study of apazunersen in Angelman syndrome, a rare, neurogenetic disorder, did not achieve its primary endpoint or its key secondary endpoint.The late-stage study did not reach the primary endpoint of change from Baseline in Bayley-4 cognitive raw score nor the key secondary endpoint of net response in Multidomain Responder Index, according to a statement.The safety profile for the phase 3 trial remained consistent with phase 1 and phase 2, the company said.Ultragenyx said it will assess the apazunersen program following this outcome and make a decision on its disposition.Shares of Ultragenyx were down about 45% in after-hours trading.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664417628","title":"Ultragenyx Pharmaceutical to Cut Costs After Drug Trial Misses Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2664417628","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664417628?lang=en_us&edition=fundamental","pubTime":"2026-09-03 05:13","pubTimestamp":1788383580,"startTime":"0","endTime":"0","summary":"Ultragenyx Pharmaceutical said it will look to reduce expenses and evaluate its development of apazunersen after the drug failed to meet its primary endpoint in a Phase 3 trial.The treatment didn't meet the primary endpoint of improving cognitive scores in patients with Angelman syndrome, a rare neuro-genetic disease, the company said. The drug also missed the study's secondary endpoint.Based on the results, Ultragenyx said it will evaluate the apazunersen program and make a decision on its future. It said it will also \"assess its planned operations to define and implement significant expense reductions, while supporting its growing commercial business.\"Shares plunged on the news, trading down 45% at $14.65 after Wednesday's bell.\"Based on everything we observed in the robust Phase 1/2 clinical development program and long-term extension study, we are disappointed by the Aspire result,\" Chief Executive Emil Kakkis said.He added that the company will focus on expanding its existing 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PharmaceuticalRARE.Osaid on Wednesday its experimental drug for a rare genetic neurodevelopmental disorder did not meet the main goal in a late-stage trial.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260902:nL4N44U1TA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RARE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664846068","title":"Ultragenyx Announces Phase 3 Aspire Results in Angelman Syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2664846068","media":"THOMSON 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NOVATO,","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/09/02/3355481/20739/en/ultragenyx-announces-phase-3-aspire-results-in-angelman-syndrome.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4135","BK4200","ASO","CNS","BK4561","RARE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2664819292","title":"Ultragenyx Unit Amlogenyx Presents at Wells Fargo Healthcare Conference Sept. 8","url":"https://stock-news.laohu8.com/highlight/detail?id=2664819292","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664819292?lang=en_us&edition=fundamental","pubTime":"2026-09-02 20:02","pubTimestamp":1788350542,"startTime":"0","endTime":"0","summary":"Ultragenyx unit Amlogenyx presents at Wells Fargo Healthcare Conference Sept. 8Ultragenyx subsidiary Amlogenyx will present at the Wells Fargo 21st Annual Healthcare Conference in Boston on Sept. 8, 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publication of Phase 3 Genglycos trial results","url":"https://stock-news.laohu8.com/highlight/detail?id=2664861817","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2664861817?lang=en_us&edition=fundamental","pubTime":"2026-09-02 04:45","pubTimestamp":1788295527,"startTime":"0","endTime":"0","summary":"Ultragenyx (RARE) announced the publication of 96-week data from its Phase 3 study of Genglycos, also known as DTX401, for the treatment of 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