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Orchestra BioMed

5.36

-0.0700-1.29%

Post-market: 5.360.00000.00%19:30 EDT

Volume:276.67K

Turnover:1.50M

Market Cap:320.96M

PE:-5.36

High:5.53

Open:5.45

Low:5.27

Close:5.43

52wk High:5.78

52wk Low:2.20

Shares:59.88M

Float Shares:33.00M

Volume Ratio:0.45

T/O Rate:0.84%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.9995

EPS(LYR):-1.1091

ROE:-397.30%

ROA:-45.73%

PB:16.61

PE(LYR):-4.83

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Overview Company News Filings

Orchestra BioMed Q1 revenue falls and misses estimates

BRIEF-Orchestra BioMed Q1 EPS USD -0.33

Orchestra Biomed Q1 EPS USD -0.33

THOMSON REUTERS

Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates

Press Release: Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates

Orchestra BioMed Q1 net loss widens 10% to $20.7 million; revenue drops 87% to $110,000

Analysts Offer Insights on Healthcare Companies: Enanta Pharmaceuticals (ENTA) and Orchestra BioMed Holdings (OBIO)

Orchestra BioMed gives clinical, regulatory update on BACKBEAT trial timeline

Orchestra BioMed targets BACKBEAT trial enrollment completion by end-Q3 2026

U.S. Earnings Preview: After Market Close May 8

Orchestra BioMed receives $15M payment from Ligand

Press Release: Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement

Orchestra Biomed Receives $20 Million Payment From Medtronic Under Previously Announced Financing Agreement

THOMSON REUTERS

Orchestra Biomed Holdings Inc expected to post a loss of 43 cents a share - Earnings Preview

Orchestra granted additional breakthrough device designation for AVIM therapy

Orchestra BioMed wins FDA Breakthrough Device designation for AVIM hypertension therapy

FDA Grants Orchestra Biomed Additional Breakthrough Device Designation for Avim Therapy

THOMSON REUTERS

RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16

Orchestra BioMed says MODERATO II trial shows 13.2 mmHg AVIM blood pressure drop

Orchestra BioMed presentation highlights pivotal trials for hypertension pacing, sirolimus artery therapy

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Release: Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates","url":"https://stock-news.laohu8.com/highlight/detail?id=2635538240","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635538240?lang=en_us&edition=fundamental","pubTime":"2026-05-13 04:18","pubTimestamp":1778617080,"startTime":"0","endTime":"0","summary":"-- Orchestra BioMed targeting enrollment completion of BACKBEAT Global. Pivotal Trial  by the end of Q3 2026. -- Medtronic  and Orchestra BioMed intend to pursue late-breaking. clinical trial presentation at major cardiology conference in Q2 2027 and. subsequent marketing application submission to FDA and global regulatory. -- FDA granted a second Breakthrough Device Designation  for AVIM. Therapy specific to patients with uncontrolled hypertension despite the. use of anti-hypertensive medications, and an indication for a pacemaker. -- Virtue Trial sites progressing with site activation and patient. -- Cash runway projected into Q4 2027 and through achievement of key. enrollment completion by the end of the third quarter of 2026 and. announced plans with Medtronic to pursue presentation of primary endpoint. cardiovascular conference in the second quarter of 2027, assuming primary. in sample size for the BACKBEAT Trial to a target total of 284","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OBIO","BK4585","LU1983299246.USD","IE00BFXG1179.USD","LU0211326839.USD","IE00BQXX3C00.GBP","LU1116320737.USD","LU2089984988.USD","LU0208291251.USD","LU0211326755.USD","LU0314106906.USD","IE00B42XCP33.USD","LU0211331839.USD","R","LU1291159041.SGD","LU1244550494.USD","LU2028103732.USD","BK4232","LU2468319806.SGD","LU0122379950.USD","LU1023059063.AUD","LU2023251221.USD","LU0158827781.USD","LU0158827948.USD","LU1116320901.HKD","BK4566","03160","LU2089283258.USD","IE00B3T34201.USD","LU2111349929.HKD","BK4604","LU0106261372.USD","LU1057294990.SGD","BK4555","BK4099","LU1061106388.HKD","LU0496365809.HKD","LU1989771016.USD","LU0070302665.USD","LU2112291526.USD","LU2271345857.HKD","IE00BGHQF631.EUR","LU0976567544.SGD","LABU","MDT","BK4588","BK4533","LU1244550221.USD","TM","LU0162691827.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635124706","title":"Orchestra BioMed Q1 net loss widens 10% to $20.7 million; revenue drops 87% to $110,000","url":"https://stock-news.laohu8.com/highlight/detail?id=2635124706","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635124706?lang=en_us&edition=fundamental","pubTime":"2026-05-13 04:15","pubTimestamp":1778616951,"startTime":"0","endTime":"0","summary":"Orchestra BioMed posted a net loss of USD 20.69 million, widening 10% from a year earlier.Revenue fell 87% to USD 110,000 as partnership revenue dropped to no revenue.Operating loss widened 17% to USD 22.08 million as research and development expense climbed 17% to USD 15.78 million.Interest expense rose to USD 821,000 from interest income a year earlier, while gain on sale of strategic investments totaled USD 2.24 million.BACKBEAT Trial enrollment completion targeted by end of Q3 2026, with primary endpoint data planned for a late-breaking presentation in Q2 2027; cash, cash equivalents and marketable securities totaled USD 94.4 million, funding operations into Q4 2027.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Orchestra Biomed H","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nNDL8chvWS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OBIO","BK4082"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634243119","title":"Analysts Offer Insights on Healthcare Companies: Enanta Pharmaceuticals (ENTA) and Orchestra BioMed Holdings (OBIO)","url":"https://stock-news.laohu8.com/highlight/detail?id=2634243119","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634243119?lang=en_us&edition=fundamental","pubTime":"2026-05-12 23:10","pubTimestamp":1778598627,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Enanta Pharmaceuticals (ENTA) and Orchestra BioMed H...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-enanta-pharmaceuticals-enta-and-orchestra-biomed-holdings-obio-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-enanta-pharmaceuticals-enta-and-orchestra-biomed-holdings-obio-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LABU","XLV","XBI","OBIO","BK4082","ENTA","LU0029874061.USD","BK4137","BK4585","BK4581","LU0128526141.USD","BK4139","HCSG","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634104992","title":"Orchestra BioMed gives clinical, regulatory update on BACKBEAT trial timeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2634104992","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634104992?lang=en_us&edition=fundamental","pubTime":"2026-05-12 22:08","pubTimestamp":1778594919,"startTime":"0","endTime":"0","summary":"Orchestra BioMed (OBIO) announced an update to the overall clinical and regulatory timeline for the BACKBEAT Trial evaluating Atrioventricular Inte...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-gives-clinical-regulatory-update-on-backbeat-trial-timeline-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-gives-clinical-regulatory-update-on-backbeat-trial-timeline-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OBIO","BK4082"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634172211","title":"Orchestra BioMed targets BACKBEAT trial enrollment completion by end-Q3 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2634172211","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634172211?lang=en_us&edition=fundamental","pubTime":"2026-05-12 20:43","pubTimestamp":1778589810,"startTime":"0","endTime":"0","summary":"Orchestra BioMed set end of Q3 2026 target to finish enrollment for BACKBEAT global pivotal trial testing AVIM Therapy in pacemaker-indicated patients with uncontrolled hypertension.Primary endpoint results have not been presented; data slated for submission as a late-breaker at a major cardiology conference in Q2 2027.Timeline update follows FDA-backed reduction in trial size, aiming to keep study on track while maintaining strength of planned readout.Assuming trial meets safety and efficacy goals, Medtronic plans to file for FDA marketing approval once primary endpoint analyses and reports are completed, then pursue additional regulatory clearances globally.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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Adjusted EPS is forecast at 96 cents.Radnet Inc.'s first-quarter EPS is forecast at a loss of 25 cents, compared with a loss of 51 cents in the prior-year period. Adjusted EPS is forecast at a loss of 16 cents.Hawaiian Electric Industries Inc.'s first-quarter EPS is forecast at 38 cents, compared with 15 cents in the prior-year period. Adjusted EPS is forecast at 27 cents.AnaptysBio Inc.'s first-quarter EPS is forecast at a loss of 74 cents, compared with a loss of $1.28 in the prior-year period. Adjusted EPS is forecast at a loss of 64 cents.Biomea Fusion Inc.'s first-quarter EPS is forecast at a loss of 28 cents, compared with a loss of 80 cents in the prior-ye","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4081","BK4196","JHG","BK4539","HE","IE00BGHQF748.EUR","ANAB","LU2065731478.USD","LU0054578231.USD","BK4135","RDNT","IE00B3QW5Z07.USD","BK4082","BK4585","BK4139","IE00B64PRP62.GBP","OBIO","BMEA"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633969821","title":"Orchestra BioMed receives $15M payment from Ligand","url":"https://stock-news.laohu8.com/highlight/detail?id=2633969821","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633969821?lang=en_us&edition=fundamental","pubTime":"2026-05-07 13:00","pubTimestamp":1778130015,"startTime":"0","endTime":"0","summary":"Orchestra BioMed (OBIO) announced the receipt of a $15M payment from Ligand (LGND) pursuant to the previously disclosed revenue participation right...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-receives-15m-payment-from-ligand-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-receives-15m-payment-from-ligand-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0566484027.USD","LGND","OBIO","BK4082","IE0009354923.USD","LU1559883803.SGD","BK4007","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633513859","title":"Press Release: Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2633513859","media":"Dow Jones","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633513859?lang=en_us&edition=fundamental","pubTime":"2026-05-06 20:01","pubTimestamp":1778068860,"startTime":"0","endTime":"0","summary":"-- $15 million payment fulfills previously scheduled tranche under. royalty-based financing agreement, bringing total capital received from. Ligand to $40 million to date in exchange for tiered royalty interest in. Orchestra BioMed's future revenue as well as equity. -- Funding supports continued execution of Orchestra BioMed's pivotal trials. -- This payment, together with a $20 million investment from Medtronic. fresh strategic capital received on May 1, 2026 under previously. \"We and Ligand designed our strategic capital partnership to align funding with execution, and the receipt of this additional tranche from Ligand reflects continued and timely progress against that plan,\" said David Hochman, Chairman and Chief Executive Officer of Orchestra BioMed. \"We congratulate Ligand on an outstanding run of recent successes in its portfolio and its continued strategic growth. We believe Orchestra BioMed's programs can contribute meaningfully to Ligand's continued royalty growth in the 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Biomed Receives $20 Million Payment From Medtronic Under Previously Announced Financing Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2633388651","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633388651?lang=en_us&edition=fundamental","pubTime":"2026-05-06 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Biomed Holdings Inc  expected to post a loss of 43 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2632647593","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632647593?lang=en_us&edition=fundamental","pubTime":"2026-05-02 04:16","pubTimestamp":1777666566,"startTime":"0","endTime":"0","summary":"Orchestra Biomed Holdings Inc  expected to post a loss of43cents a share - Earnings Preview Orchestra Biomed Holdings Inc OBIO.OQ OBIO.O is expected to  show a fall in quarterly revenue when it 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BioMed (OBIO) announced that the FDA has granted a second breakthrough device designation, or BDD, for AVIM therapy specific to patients ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/orchestra-granted-additional-breakthrough-device-designation-for-avim-therapy-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/orchestra-granted-additional-breakthrough-device-designation-for-avim-therapy-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LABU","BK4588","BK4082","OBIO","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631640630","title":"Orchestra BioMed wins FDA Breakthrough Device designation for AVIM hypertension therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2631640630","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631640630?lang=en_us&edition=fundamental","pubTime":"2026-04-30 21:01","pubTimestamp":1777554082,"startTime":"0","endTime":"0","summary":"FDA granted Orchestra BioMed second Breakthrough Device Designation for AVIM Therapy in pacemaker-indicated patients with uncontrolled hypertension despite medication.Combined designations cover more than 7.7 million US adults with hypertension despite medication.Decision supports accelerated review path for AVIM Therapy, which is being evaluated in BACKBEAT global pivotal trial run with Medtronic.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nNDLbZ8QHR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0496365809.HKD","LU1983299246.USD","LU0314104364.USD","LU1244550577.SGD","LU1244550221.USD","LU1023059063.AUD","OBIO","LU0211326755.USD","IE00BFXG1179.USD","IE00BN0W2V16.EUR","LU0122379950.USD","SG9999014039.USD","IE00BQXX3D17.EUR","IE00BDGV0183.EUR","LU1116320737.USD","IE00BGHQF631.EUR","LU2028103732.USD","LU1291159041.SGD","SG9999014005.SGD","LU1989764748.USD","LU0006306889.USD","BK4585","LU2111349929.HKD","LU0211326839.USD","BK4588","IE00B64PRP62.GBP","LU1057294990.SGD","LU0158827781.USD","SG9999014021.USD","LU2271345857.HKD","LU0211331839.USD","BK4533","LU1506573853.SGD","LU0432979614.USD","NDAQ","LU0072461881.USD","LU0162691827.USD","LU0976567544.SGD","LU1061106388.HKD","IE000M9KFDE8.USD","LU0070302665.USD","IE00BN0W2T93.GBP","LU1989771016.USD","LU2089283258.USD","MDT","LU2112291526.USD","LU1571399168.USD","LU0265550946.USD","LU0158827948.USD","BK4566"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631630504","title":"FDA Grants Orchestra Biomed Additional Breakthrough Device Designation for Avim Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2631630504","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631630504?lang=en_us&edition=fundamental","pubTime":"2026-04-30 21:00","pubTimestamp":1777554004,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nTUA4MHPQT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU2028103732.USD","LU0211326755.USD","LU1291159041.SGD","LU0072461881.USD","LU1989764664.SGD","IE00BGHQF631.EUR","IE00B3T34201.USD","LU0122379950.USD","OBIO","IE00BVYPNV92.GBP","LU0976567544.SGD","LU0320765489.SGD","LU2089284900.SGD","BK4082","LU2111349929.HKD","MDT","BK4566","LU2089984988.USD","LU1244550494.USD","LU0162691827.USD","IE00B3PB1722.GBP","LU0106261372.USD","LU2112291526.USD","LU1989771016.USD","LU0265550946.USD","IE00BQXX3F31.USD","LU1244550577.SGD","LU1244550221.USD","IE00BQXX3C00.GBP","LU0006306889.USD","LU0070302665.USD","LU1571399168.USD","LU2023251221.USD","LU0158827948.USD","LU2468319806.SGD","IE00BDGV0183.EUR","IE000M9KFDE8.USD","IE00BVYPNW00.USD","IE00BFXG1179.USD","LU1023059063.AUD","LU1989764748.USD","LU1506573853.SGD","LU2271345857.HKD","LU0496365809.HKD","LU0158827781.USD","LU1983299246.USD","LU1116320737.USD","BK4533","LU2089283258.USD","LU1057294990.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631227505","title":"RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16","url":"https://stock-news.laohu8.com/highlight/detail?id=2631227505","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631227505?lang=en_us&edition=fundamental","pubTime":"2026-04-30 05:47","pubTimestamp":1777499242,"startTime":"0","endTime":"0","summary":"RTW Investments reported exercise of pre-funded warrants into 1,250,032 Orchestra BioMed common shares on April 27, 2026.Issuer withheld 32 shares to cover exercise price, leaving 1,250,000 shares issued to RTW funds.RTW funds reported 9,556,063 Orchestra BioMed common shares beneficially owned following transactions.Pre-funded warrants were reported at an exercise price of $0.0001 per share.RTW funds reported 2,386,331 pre-funded warrants beneficially owned following transaction.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Orchestra Biomed Holdings Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260429:nNDL15nlRn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4082","OBIO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629562188","title":"Orchestra BioMed says MODERATO II trial shows 13.2 mmHg AVIM blood pressure drop","url":"https://stock-news.laohu8.com/highlight/detail?id=2629562188","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629562188?lang=en_us&edition=fundamental","pubTime":"2026-04-24 00:01","pubTimestamp":1776960085,"startTime":"0","endTime":"0","summary":"Orchestra BioMed flagged new clinical and mechanistic data for its Atrioventricular Interval Modulation  Therapy, slated for presentation at Heart Rhythm Society  2026.Pre-randomization set-up results from MODERATO II showed blood pressure fell immediately for most patients following therapy activation.Six-month follow-up indicated many patients maintained blood pressure control, supporting potential durability of effect in an older, higher-risk population.Separate pressure-volume loop findings, already published in JACC: Clinical Electrophysiology, showed AVIM lowered systolic blood pressure versus standard pacing while preserving overall heart pumping strength.Orchestra BioMed highlighted BACKBEAT Global Pivotal Trial enrollment with Medtronic, positioning upcoming readouts as key validation for broader commercialization.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260423:nNDLb8Rc7x:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BN0W2T93.GBP","OBIO","BK4585","IE000M9KFDE8.USD","IE00BFXG1179.USD","IE00BQXX3F31.USD","IE00BQXX3C00.GBP","LU0211326839.USD","LU0320765489.SGD","LU1116320737.USD","LU1244550577.SGD","LU0314104364.USD","LU2089984988.USD","SG9999014021.USD","IE00B3PB1722.GBP","IE00B42XCP33.USD","LU1571399168.USD","LU2210149790.SGD","BK4082","IE00BQXX3D17.EUR","LU0072461881.USD","BK4112","LU0006306889.USD","SG9999014005.SGD","IE00B3QW5Z07.USD","LU0122379950.USD","LU1023059063.AUD","LU0158827781.USD","IE00BGHQF748.EUR","NDAQ","LU1116320901.HKD","LU0432979614.USD","LU2210150020.SGD","IE00B3T34201.USD","LU2111349929.HKD","LU0265550359.USD","LU0106261372.USD","LU1061106388.HKD","LU0496365809.HKD","LU1989771016.USD","LU2112291526.USD","IE00BVYPNV92.GBP","LU2271345857.HKD","LU0976567544.SGD","LU2089284900.SGD","IE00BVYPNW00.USD","MDT","BK4588","BK4533","LU2095319765.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625677137","title":"Orchestra BioMed presentation highlights pivotal trials for hypertension pacing, sirolimus artery therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2625677137","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625677137?lang=en_us&edition=fundamental","pubTime":"2026-04-06 22:59","pubTimestamp":1775487592,"startTime":"0","endTime":"0","summary":"Orchestra BioMed outlined two pivotal-stage cardiovascular programs, AVIM Therapy for uncontrolled hypertension in pacemaker-indicated patients and Virtue SAB for atherosclerotic artery disease.AVIM Therapy BACKBEAT global pivotal trial is actively enrolling up to 500 patients across about 130 sites, with primary efficacy endpoint based on change in mean 24-hour ambulatory systolic blood pressure at 3 months.Virtue SAB U.S. pivotal Virtue Trial is actively enrolling 740 coronary in-stent restenosis patients in a 1:1 randomized study versus Boston Scientific AGENT paclitaxel-coated balloon, with primary endpoint target lesion failure at 12 months.Orchestra BioMed cited cash runway into Q4 2027, with $35 million in committed tranche payments from Medtronic and Ligand and up to $21 million expected from Haemonetics acquisition of Vivasure Medical.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260406:nNDL43xDhr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2491049909.HKD","LU1169589451.USD","LU2506952097.USD","MDT","IE00B4R5TH58.HKD","LU0823417737.USD","LU0211326839.USD","LU0314106906.USD","LU1061106388.HKD","LU0528227936.USD","IE00B64QTZ34.USD","LU0106261612.USD","LU2244417387.USD","BK4504","LU0012050646.USD","LU1244550494.USD","LU0158827948.USD","IE00B3T34201.USD","LU2506951875.HKD","LU0238689110.USD","LU1989772840.SGD","LU0432979614.USD","LU1720051017.SGD","BK4588","LU2242649171.HKD","HAE","OBIO","LU0122379950.USD","LU1804176565.USD","LU2112291526.USD","LU0823416689.USD","LU0882574055.USD","LU2089284900.SGD","LU1791710400.SGD","BSX","IE00BVYPNV92.GBP","LU2271345857.HKD","IE00B19Z6F94.USD","IE00BQXX3F31.USD","LU0187121727.USD","BK4533","LU0353189680.USD","BK4581","LU1718418525.SGD","LU0976567544.SGD","LU0345769128.USD","LU0158827781.USD","LU1244550221.USD","IE00BJT1NW94.SGD","IE00B42XCP33.USD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":3,"totalSize":72,"code":"91000000","status":"200"}]}}