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Karyopharm Therapeutics

1.96

+0.14007.69%

Post-market: 1.95-0.0099-0.51%19:53 EDT

Volume:876.77K

Turnover:1.68M

Market Cap:44.42M

PE:-0.15

High:1.97

Open:1.85

Low:1.82

Close:1.82

52wk High:10.99

52wk Low:1.79

Shares:22.66M

Float Shares:17.07M

Volume Ratio:0.86

T/O Rate:5.14%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-13.0816

EPS(LYR):-17.9300

ROE:-891.05%

ROA:-47.61%

PB:-0.13

PE(LYR):-0.11

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Overview Company News Filings

Karyopharm Therapeutics Slides on Disclosure of Cash-retention Program for Executives

Karyopharm Grants 1,649 Rsus to Four New Hires Under Inducement Plan

Karyopharm Therapeutics Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

THOMSON REUTERS

Analysts Are Bullish on These Healthcare Stocks: BioAge Labs, Inc. (BIOA), Karyopharm Therapeutics (KPTI)

Karyopharm posts Phase 3 SENTRY trial presentation on selinexor plus ruxolitinib in myelofibrosis

Karyopharm posts endometrial cancer treatment landscape presentation

Karyopharm joins Cantor-hosted webcast featuring endometrial cancer KOL Robert Coleman

Karyopharm says Phase 3 SENTRY trial selected for presentation at EHA 2026

Karyopharm to Report Data From Phase 3 Trial of Selinexor Plus Ruxolitinib in Myelofibrosis

MT Newswires Live

Karyopharm’s selinexor combination shows efficacy in myelofibrosis

Karyopharm's Phase 3 Sentry Trial of Selinexor Plus Ruxolitinib in Myelofibrosis Selected for Late-Breaking Oral Presentation at Eha 2026

THOMSON REUTERS

Karyopharm says Phase 3 SENTRY trial shows selinexor-ruxolitinib combo lifts SVR35 in myelofibrosis

Karyopharm grants 1,200 RSUs to newly hired employee under inducement plan

Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(C)(4)

THOMSON REUTERS

Karyopharm to discuss Phase 3 SENTRY trial results for selinexor plus ruxolitinib in myelofibrosis at June 2 call

Karyopharm Therapeutics shareholders approve 3 million-share increase to 2022 equity plan at annual meeting

Karyopharm management participates in Jefferies Global Healthcare Conference fireside chat

Karyopharm (KPTI) Leans on SENTRY in Pivotal Call

Karyopharm publishes corporate presentation highlighting selinexor Phase 3 trial readouts in 2026

Karyopharm Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

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Therapeutics Slides on Disclosure of Cash-retention Program for Executives","url":"https://stock-news.laohu8.com/highlight/detail?id=2652233925","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652233925?lang=en_us&edition=fundamental","pubTime":"2026-07-18 06:14","pubTimestamp":1784326440,"startTime":"0","endTime":"0","summary":"Shares of Karyopharm Therapeutics fell after the company launched a cash-retention program for executives.The stock slipped 21%, to $7.50, in after-hours trading Friday, after closing up 1.4%, at $9.51. At close, the stock had risen 29% year-to-date.Under the program, Chief Executive Officer Richard Paulson will receive a cash retention award of more than $1.7 million, the company disclosed in a Friday filing with the Securities and Exchange Commission.Chief Medical Officer and Head of Research Reshma Rangwala will receive $725,000, Chief Development Officer Stuart Poulton will get $640,000, and Chief Financial Officer Lori Macomber will get $625,000.\"The purpose of the 2026 Leadership Cash Retention Program is to incentivize retention of key employees during a period in which the Company is expecting several meaningful catalysts requiring the continued experience and expertise of the designated employees,\" the company said in its filing.Write to Elias Schisgall at elias.schisgall@wsj.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648525264","title":"Karyopharm Grants 1,649 Rsus to Four New Hires Under Inducement Plan","url":"https://stock-news.laohu8.com/highlight/detail?id=2648525264","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648525264?lang=en_us&edition=fundamental","pubTime":"2026-07-02 04:06","pubTimestamp":1782936384,"startTime":"0","endTime":"0","summary":"Karyopharm grants 1,649 RSUs to four new hires under inducement planKaryopharm Therapeutics granted 1,649 restricted stock units to four newly hired employees under its 2022 Inducement Stock Incentive","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260701:nNDLbhZgvy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648352547","title":"Karyopharm Therapeutics Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2648352547","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648352547?lang=en_us&edition=fundamental","pubTime":"2026-07-02 04:05","pubTimestamp":1782936300,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260701:nTUA75RZN2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644741614","title":"Analysts Are Bullish on These Healthcare Stocks: BioAge Labs, Inc. (BIOA), Karyopharm Therapeutics (KPTI)","url":"https://stock-news.laohu8.com/highlight/detail?id=2644741614","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644741614?lang=en_us&edition=fundamental","pubTime":"2026-06-17 21:30","pubTimestamp":1781703053,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on BioAge Labs, Inc. (BIOA), Karyopharm Therapeutics (K...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-are-bullish-on-these-healthcare-stocks-bioage-labs-inc-bioa-karyopharm-therapeutics-kpti-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-are-bullish-on-these-healthcare-stocks-bioage-labs-inc-bioa-karyopharm-therapeutics-kpti-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BIOA","BK4007","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2643246520","title":"Karyopharm posts Phase 3 SENTRY trial presentation on selinexor plus ruxolitinib in myelofibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2643246520","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2643246520?lang=en_us&edition=fundamental","pubTime":"2026-06-14 16:14","pubTimestamp":1781424853,"startTime":"0","endTime":"0","summary":"Karyopharm published Phase 3 SENTRY trial results evaluating selinexor with ruxolitinib in JAK inhibitor-nave myelofibrosis.Combination delivered rapid, deeper, sustained spleen volume reduction versus ruxolitinib alone, with consistent effects across subgroups.Symptom improvement was similar between arms, with meaningful reductions from baseline.Overall survival signal reported; spleen volume reduction linked with improved survival.Safety described as manageable, consistent with known profiles of both drugs.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on June 14, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260614:nNDL4sLjbX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642433662","title":"Karyopharm posts endometrial cancer treatment landscape presentation","url":"https://stock-news.laohu8.com/highlight/detail?id=2642433662","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642433662?lang=en_us&edition=fundamental","pubTime":"2026-06-09 00:04","pubTimestamp":1780934643,"startTime":"0","endTime":"0","summary":"Karyopharm published an endometrial cancer treatment landscape update centered on selinexor as an oral XPO1 inhibitor in maintenance therapy.Highlights SIENDO Phase 3 exploratory TP53 wild-type subgroup: median PFS 13.7 months vs 3.7 months; HR 0.41; P=0.002.Reports longer-term follow-up in TP53 wild-type: median PFS 28.4 months vs 5.2 months; HR 0.44; data cutoff April 1, 2024.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on June 08, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nNDL8Gshr7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640918166","title":"Karyopharm joins Cantor-hosted webcast featuring endometrial cancer KOL Robert Coleman","url":"https://stock-news.laohu8.com/highlight/detail?id=2640918166","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640918166?lang=en_us&edition=fundamental","pubTime":"2026-06-04 04:15","pubTimestamp":1780517756,"startTime":"0","endTime":"0","summary":"Karyopharm will join a Cantor-hosted virtual fireside chat on June 8, 2026 at 12:00 p.m. ET.Discussion will feature senior management alongside Robert Coleman, principal investigator of the Phase 3 XPORT-EC-042 endometrial cancer trial.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260603:nNDL2kKBBk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640494268","title":"Karyopharm says Phase 3 SENTRY trial selected for presentation at EHA 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2640494268","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640494268?lang=en_us&edition=fundamental","pubTime":"2026-06-03 00:02","pubTimestamp":1780416139,"startTime":"0","endTime":"0","summary":"Karyopharm (KPTI) Therapeutics announced that its late-breaking abstract was accepted for an oral presentation at the 2026 European Hematology Asso...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/karyopharm-says-phase-3-sentry-trial-selected-for-presentation-at-eha-2026-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/karyopharm-says-phase-3-sentry-trial-selected-for-presentation-at-eha-2026-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["EPV","KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640194481","title":"Karyopharm to Report Data From Phase 3 Trial of Selinexor Plus Ruxolitinib in Myelofibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2640194481","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640194481?lang=en_us&edition=fundamental","pubTime":"2026-06-02 23:21","pubTimestamp":1780413677,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics  said Tuesday that a late-breaking abstract from its phase 3 trial of selinexor combined with ruxolitinib in myelofibrosis was accepted for an oral presentation at the 2026 European Hematology Association Congress in mid-June.The company said new data will highlight a post-hoc analysis of 24 patients from phase 1 of the trial, which indicates that achieving a spleen volume reduction of 35% or more may predict overall survival, consistent with a similar analysis from the phase 3 trial.Shares of Karyopharm Therapeutics were down more than 8% in Tuesday trading.Price: 8.99, Change: -0.84, Percent Change: -8.50","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640414859","title":"Karyopharm’s selinexor combination shows efficacy in myelofibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2640414859","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640414859?lang=en_us&edition=fundamental","pubTime":"2026-06-02 22:47","pubTimestamp":1780411648,"startTime":"0","endTime":"0","summary":"Karyopharm (KPTI) will present the results of its Phase 3 SENTRY trial in a presentation at the 2026 ASCO Annual Meeting. The SENTRY results were a...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/karyopharms-selinexor-combination-shows-efficacy-in-myelofibrosis-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/karyopharms-selinexor-combination-shows-efficacy-in-myelofibrosis-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640946247","title":"Karyopharm's Phase 3 Sentry Trial of Selinexor Plus Ruxolitinib in Myelofibrosis Selected for Late-Breaking Oral Presentation at Eha 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2640946247","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640946247?lang=en_us&edition=fundamental","pubTime":"2026-06-02 22:03","pubTimestamp":1780408989,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260602:nTUA8BV5GS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640943739","title":"Karyopharm says Phase 3 SENTRY trial shows selinexor-ruxolitinib combo lifts SVR35 in myelofibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2640943739","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640943739?lang=en_us&edition=fundamental","pubTime":"2026-06-02 21:00","pubTimestamp":1780405228,"startTime":"0","endTime":"0","summary":"Karyopharm will present Phase 3 SENTRY data at ASCO 2026; results were published simultaneously in the Journal of Clinical Oncology.Selinexor with ruxolitinib improved spleen response versus ruxolitinib alone, supporting a stronger efficacy profile for first-line myelofibrosis.Symptom improvement was broadly similar between arms, reducing the likelihood of a differentiated patient-reported benefit.Overall survival trended in favor of the combination, an outcome that could strengthen the regimen’s commercial positioning if confirmed.Safety was described as manageable with no new signals, though severe side effects were more frequent with the combination.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260602:nNDL6d5cGc:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640964519","title":"Karyopharm grants 1,200 RSUs to newly hired employee under inducement plan","url":"https://stock-news.laohu8.com/highlight/detail?id=2640964519","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640964519?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:07","pubTimestamp":1780344463,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics granted 1,200 restricted stock units to one newly hired employee under its 2022 Inducement Stock Incentive Plan.The award was granted on May 31, 2026.Vesting is scheduled over three years, with 33 1/3% vesting on each anniversary of the grant date, subject to continued service.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDL803Yhv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640964804","title":"Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(C)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2640964804","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640964804?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:05","pubTimestamp":1780344302,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nTUA8HMCLL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640253956","title":"Karyopharm to discuss Phase 3 SENTRY trial results for selinexor plus ruxolitinib in myelofibrosis at June 2 call","url":"https://stock-news.laohu8.com/highlight/detail?id=2640253956","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640253956?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:32","pubTimestamp":1780313562,"startTime":"0","endTime":"0","summary":"Karyopharm scheduled a June 2, 2026 investor call to discuss Phase 3 SENTRY results for selinexor with ruxolitinib in myelofibrosis.The data were presented at the 2026 ASCO Annual Meeting in an oral session led by principal investigator John Mascarenhas.The update highlights the combination’s clinical performance in myelofibrosis, informing the program’s next regulatory and commercial steps.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on June 01, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDL3WjdHt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639162706","title":"Karyopharm Therapeutics shareholders approve 3 million-share increase to 2022 equity plan at annual meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2639162706","media":"Reuters","labels":["executive","shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639162706?lang=en_us&edition=fundamental","pubTime":"2026-05-29 04:25","pubTimestamp":1779999929,"startTime":"0","endTime":"0","summary":"Karyopharm held its annual stockholder meeting on May 21, 2026.Stockholders backed an amendment to the 2022 Equity Incentive Plan, lifting the share reserve by 3 million shares for future issuance.Stockholders also endorsed an amendment to the employee stock purchase plan, increasing the share pool by 1.4 million shares.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 28, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260528:nNDL9j4t8n:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive,shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638660486","title":"Karyopharm management participates in Jefferies Global Healthcare Conference fireside chat","url":"https://stock-news.laohu8.com/highlight/detail?id=2638660486","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638660486?lang=en_us&edition=fundamental","pubTime":"2026-05-28 19:31","pubTimestamp":1779967877,"startTime":"0","endTime":"0","summary":"Karyopharm will take part in the 2026 Jefferies Global Healthcare Conference on June 4, 2026.Senior management is scheduled for a fireside chat at 8:10 a.m. ET in New York.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260528:nNDL1srlW3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636903868","title":"Karyopharm (KPTI) Leans on SENTRY in Pivotal Call","url":"https://stock-news.laohu8.com/highlight/detail?id=2636903868","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636903868?lang=en_us&edition=fundamental","pubTime":"2026-05-20 12:38","pubTimestamp":1779251894,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics INC (($KPTI)) has held its Q1 earnings call. Read on for the main highlights of the call. Karyopharm Therapeutics struck an...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/karyopharm-kpti-leans-on-sentry-in-pivotal-call?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/karyopharm-kpti-leans-on-sentry-in-pivotal-call?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636992009","title":"Karyopharm publishes corporate presentation highlighting selinexor Phase 3 trial readouts in 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2636992009","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636992009?lang=en_us&edition=fundamental","pubTime":"2026-05-19 04:32","pubTimestamp":1779136357,"startTime":"0","endTime":"0","summary":"Karyopharm highlighted Phase 3 SENTRY topline data in JAK inhibitor-nave myelofibrosis, showing selinexor with ruxolitinib met the co-primary endpoint on spleen volume reduction at week 24.SVR35 at week 24 was 49.8% for selinexor with ruxolitinib versus 28% for placebo with ruxolitinib, with an odds ratio of 2.58; p<0.0001.The symptom co-primary endpoint missed, with an adjusted mean difference of 0.97 in absolute total symptom score change at week 24; p=0.8246.Secondary analyses showed an overall survival signal with a hazard ratio of 0.43; nominal p=0.0222, with 11 deaths in the combination arm versus 12 in the control arm.Topline results were also flagged as expected mid-2026 from the Phase 3 XPORT-EC-042 trial of selinexor in TP53 wild-type endometrial cancer.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes o","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260518:nNDL96dpC8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635774988","title":"Karyopharm Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2635774988","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635774988?lang=en_us&edition=fundamental","pubTime":"2026-05-14 23:10","pubTimestamp":1778771444,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc reports results for the quarter ended March 31 - Earnings SummaryKaryopharm Therapeutics Inc KPTI.OQ reported a quarterly adjusted loss of $1.24 per share for the quarter e","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260514:nL8N41R1TK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":6,"pageCount":3,"totalSize":110,"code":"91000000","status":"200"}]}}