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Charles River Laboratories

295.19

+3.741.28%

Post-market: 295.190.00000.00%19:38 EDT

Volume:887.56K

Turnover:262.16M

Market Cap:14.09B

PE:-60.47

High:298.18

Open:291.78

Low:289.07

Close:291.45

52wk High:299.32

52wk Low:144.26

Shares:47.74M

Float Shares:47.20M

Volume Ratio:1.02

T/O Rate:1.88%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-4.8814

EPS(LYR):-2.9122

ROE:-7.52%

ROA:4.11%

PB:4.96

PE(LYR):-101.36

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Overview Company News Filings

Grace Therapeutics Provides Regulatory Update on New Drug Application for GTx-104

Revvity Falls 15.5%, Bio-Techne Drops 10.1%, IQVIA Drops 8.3%, Charles River Down 7%

THOMSON REUTERS

Shares of Biotech and Medical Equipment Cos Fall After Thermo Fisher Results, Outlook

THOMSON REUTERS

Charles River Laboratories International Inc. Stock Underperforms Tuesday When Compared To Competitors

Charles River reports results of restrospective analysis on VCGs in toxicology

Charles River analysis finds virtual control groups match NOAEL outcomes in toxicology studies

Is Cheaper Energy and Shipping Altering The Investment Case For Charles River Laboratories (CRL)?

Simply Wall St.

GPT-Rosalind Sparks CRO Sector Slump: Should Investors Buy the Dip or Exit Amid AI Drug R&D Impact?

Charles River Laboratories International Inc. Stock Underperforms Thursday When Compared To Competitors

Charles River Labs sets first-quarter earnings release, conference call

Charles River Labs : Barclays Raises Target Price to $210 From $200

THOMSON REUTERS

Charles River Labs Is Maintained at Overweight by Barclays

Charles River Laboratories Positioned as 'Leading' CRO as Preclinical R&D Inflection Nears, RBC Says

MT Newswires Live

RBC Initiates Charles River Laboratories International at Outperform With $215 Price Target

MT Newswires Live

Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day

FDA Rejection Sparks Questions On Replimune Drug Approval Path

Benzinga_recent_news

Earnings Season Is Here. Microsoft and 7 More Companies That Usually Deliver. -- Barrons.com

Replimune says FDA’s CRL for RP1 ‘disappointing’

Replimune says FDA ‘appears to have contradicted their positions’ in CRL

Replimune downgraded to Neutral at Piper Sandler after second CRL

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River Laboratories International Inc. Stock Underperforms Tuesday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2629063255","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629063255?lang=en_us&edition=fundamental","pubTime":"2026-04-22 05:16","pubTimestamp":1776806160,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slid 1.32% to $183.10 Tuesday, on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index  falling 0.63% to 7,064.01 and Dow Jones Industrial Average  falling 0.59% to 49,149.38.The stock's fall snapped a two-day winning streak.Charles River Laboratories International Inc. closed 20.00% below its 52-week high of $228.88, which the company reached on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Tuesday, as Labcorp Holdings Inc.  rose 1.57% to $273.42, Alnylam Pharmaceuticals Inc.  fell 0.81% to $308.43, and Bio-Techne Corp.  fell 1.50% to $59.67.Data source: Dow Jones Market Data, FactSet. Data compiled April 21, 2026.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629003200","title":"Charles River reports results of restrospective analysis on VCGs in toxicology","url":"https://stock-news.laohu8.com/highlight/detail?id=2629003200","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629003200?lang=en_us&edition=fundamental","pubTime":"2026-04-21 21:34","pubTimestamp":1776778476,"startTime":"0","endTime":"0","summary":"Charles River (CRL) Laboratories International has shared the results of a retrospective analysis in Regulatory Toxicology and Pharmacology, showin...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/charles-river-reports-results-of-restrospective-analysis-on-vcgs-in-toxicology-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/charles-river-reports-results-of-restrospective-analysis-on-vcgs-in-toxicology-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0029874061.USD","BK4588","BK4530","CRL","BK4121","IE00BFMHRM44.USD","LU1815336091.USD","LU0757428866.USD","LU0128526141.USD","LU0390134368.USD","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629903673","title":"Charles River analysis finds virtual control groups match NOAEL outcomes in toxicology studies","url":"https://stock-news.laohu8.com/highlight/detail?id=2629903673","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629903673?lang=en_us&edition=fundamental","pubTime":"2026-04-21 20:05","pubTimestamp":1776773148,"startTime":"0","endTime":"0","summary":"Charles River published retrospective analysis showing virtual control groups can replace concurrent control groups in 20 toxicology studies without changing core study conclusions.Review reported 100% concordance in No Observed Adverse Effect Level across all studies.Endpoint-level differences emerged between virtual controls and concurrent controls, prompting ongoing model refinement with clients.Program targets up to 25% reduction in control-group animal use where scientifically appropriate.European Medicines Agency issued draft qualification focused on virtual control groups in non-GLP rat dose-range finding repeated-dose toxicity studies.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Charles River Laboratories International Inc. 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Initial users include pharmaceutical giant Amgen (AMGN), vaccine manufacturer Moderna (MRNA), and the Allen Institute. Following the announcement, the CRO sector saw a broad decline, with IQVIA Holdings (IQV) falling 3.5% and Charles River Laboratories (CRL) dropping 2.6%. 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River Laboratories International Inc. Stock Underperforms Thursday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2628244858","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2628244858?lang=en_us&edition=fundamental","pubTime":"2026-04-17 05:18","pubTimestamp":1776374280,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slid 2.00% to $176.94 Thursday, on what proved to be an all-around favorable trading session for the stock market, with the S&P 500 Index  rising 0.26% to 7,041.28 and the Dow Jones Industrial Average  rising 0.24% to 48,578.72.The stock's fall snapped a seven-day winning streak.Charles River Laboratories International Inc. closed 22.69% short of its 52-week high of $228.88, which the company achieved on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Thursday, as Labcorp Holdings Inc.  fell 0.14% to $266.36, Alnylam Pharmaceuticals Inc.  fell 3.98% to $320.13, and Bio-Techne Corp.  fell 1.93% to $57.36.Trading volume  remained 173,353 below its 50-day average volume of 1.1 M.Data source: Dow Jones Market Data, FactSet. Data compiled April 16, 2026.This content was created by MarketWatc","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627290308","title":"Charles River Labs sets first-quarter earnings release, conference call","url":"https://stock-news.laohu8.com/highlight/detail?id=2627290308","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627290308?lang=en_us&edition=fundamental","pubTime":"2026-04-16 20:00","pubTimestamp":1776340857,"startTime":"0","endTime":"0","summary":"Charles River Laboratories will report first-quarter 2026 results on May 7, before U.S. market open.Management will host earnings conference call May 7 at 8:30 a.m. ET.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260416:nNDL2FdnnB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","IE00BFMHRM44.USD","CRL","BK4530","LU0390134368.USD","BK4121","LU0128526141.USD","LU0757428866.USD","LU1815336091.USD","LU0029874061.USD","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627283952","title":"Charles River Labs : Barclays Raises Target Price to $210 From $200","url":"https://stock-news.laohu8.com/highlight/detail?id=2627283952","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627283952?lang=en_us&edition=fundamental","pubTime":"2026-04-15 18:22","pubTimestamp":1776248530,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260415:nAZN4SQX7V:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0390134368.USD","BK4588","IE00BFMHRM44.USD","BK4530","LU0128526141.USD","LU0029874061.USD","LU0757428866.USD","CRL","BK4585","LU1815336091.USD","BK4121"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627422533","title":"Charles River Labs Is Maintained at Overweight by Barclays","url":"https://stock-news.laohu8.com/highlight/detail?id=2627422533","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627422533?lang=en_us&edition=fundamental","pubTime":"2026-04-15 05:10","pubTimestamp":1776201000,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/CRL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 14, 2026 17:10 ET (21:10 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0757428866.USD","LU0029874061.USD","BK4588","LU0128526141.USD","IE00BFMHRM44.USD","BK4530","CRL","BK4121","LU1815336091.USD","LU0390134368.USD","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627440868","title":"Charles River Laboratories Positioned as 'Leading' CRO as Preclinical R&D Inflection Nears, RBC Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2627440868","media":"MT Newswires 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This expected increase in spending should benefit drive outsourcing to CROs and benefit Charles River Laboratories, the brokerage noted.Charles River Laboratories could also see an opportunity in the ongoing evolution of new alternative methods or NAMs, depending on the company's adoption of NAMS, RBC said.RBC initiated coverage on Charles River Laboratories International with an outperform rating and $215 price target.Price: 181.87, Change: +3.53, Percent Change: +1.98","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4588","BK7095","BK4121","CRL","IE00BFMHRM44.USD","LU0128526141.USD","LU0757428866.USD","LU1815336091.USD","LU0390134368.USD","CRL.AU","BK4530","BK4585","LU0029874061.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627417939","title":"RBC Initiates Charles River Laboratories International at Outperform With $215 Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2627417939","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627417939?lang=en_us&edition=fundamental","pubTime":"2026-04-14 18:32","pubTimestamp":1776162740,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of overweight and mean price target of $203.93, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627466129","title":"Charles River Laboratories International Inc. Stock Outperforms Competitors On Strong Trading Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2627466129","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627466129?lang=en_us&edition=fundamental","pubTime":"2026-04-14 05:18","pubTimestamp":1776115080,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  advanced 1.53% to $178.34 Monday, on what proved to be an all-around great trading session for the stock market, with the S&P 500 Index  rising 1.02% to 6,886.24 and the Dow Jones Industrial Average  rising 0.63% to 48,218.25.This was the stock's fifth consecutive day of gains.Charles River Laboratories International Inc. closed 22.08% below its 52-week high of $228.88, which the company reached on January 13th.The stock demonstrated a mixed performance when compared to some of its competitors Monday, as Labcorp Holdings Inc.  rose 1.25% to $264.18, Alnylam Pharmaceuticals Inc.  rose 3.38% to $333.00, and Bio-Techne Corp.  rose 3.58% to $57.53.Trading volume  remained 429,499 below its 50-day average volume of 1.1 M.Data source: Dow Jones Market Data, FactSet. Data compiled April 13, 2026.This content was created by MarketWatch, which","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627506734","title":"FDA Rejection Sparks Questions On Replimune Drug Approval Path","url":"https://stock-news.laohu8.com/highlight/detail?id=2627506734","media":"Benzinga_recent_news","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627506734?lang=en_us&edition=fundamental","pubTime":"2026-04-14 01:44","pubTimestamp":1776102240,"startTime":"0","endTime":"0","summary":"Replimune gets FDA CRL for RP1 melanoma therapy, disputes review process as analysts cut ratings and price targets sharply.","market":"sh","thumbnail":"https://cdn.benzinga.com/files/images/story/2026/04/13/Motala--Sweden--7-January-2023-Fda-Logo-.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2026/04/13/Motala--Sweden--7-January-2023-Fda-Logo-.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/analyst-stock-ratings/downgrades/26/04/51788005/fda-rejection-sparks-questions-on-replimune-drug-approval-path","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/analyst-stock-ratings/downgrades/26/04/51788005/fda-rejection-sparks-questions-on-replimune-drug-approval-path","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["LU0757428866.USD","BK4530","LABU","LU0128526141.USD","REPL","BK4121","BK4585","LU0390134368.USD","LU1815336091.USD","CRL","BK4588","IE00BFMHRM44.USD","BK4139","LU0029874061.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627454118","title":"Earnings Season Is Here. 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The three major U.S. stock indexes still haven't recovered all of their pre-Iran war losses, and rallies have run into waves of selling.With earnings season beginning this week, even companies that beat profit estimates could see their stocks suffer if management teams refrain from providing guidance, given demand uncertainty amid higher oil prices and limited supplies.These guardrails yield the following list of names: Nvidia, Microsoft, Adobe, software provider Workday, Intuit, maker of connectors Amphenol, medical device maker Boston Scientific, and Charles River Laboratories, a contract research organization for drug development.Overall, the best strategy for these stocks is to buy all or almost all of them. Buying just one or two means taking on more single-stock risk. It's difficult to know which individual names will 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