Movement Alert|ZAI LAB Rises 5.02% in Regular Trading, Efgartigimod Phase 3 Trial in Autoimmune Myositis Achieves Positive Results

Market Focus
Aug 20

On August 20, ZAI LAB rose 5.02% in regular trading, trading at HKD 21.34/share, with turnover of HKD 168 million.

On the news front, partner argenx announced on August 17 that its core product, FcRn antagonist efgartigimod, achieved positive topline results in the ALKIVIA Phase 3 clinical study for the treatment of adult autoimmune myositis. argenx has previously granted ZAI LAB exclusive rights to develop and commercialize efgartigimod in Greater China, and ZAI LAB participated in the Greater China clinical development and patient enrollment for this global study.

Clinical data showed patient improvement was evident early in treatment and sustained throughout the study period, with highly consistent treatment effects observed across both immune-mediated necrotizing myopathy and dermatomyositis subgroups. If this indication receives subsequent regulatory approval, ZAI LAB is expected to further expand efgartigimod's commercial footprint in China's autoimmune disease market. Notably, major shareholder RTW Investments recently increased its stake by approximately 4.77 million shares at USD 25.41 per share, reflecting institutional confidence in the company's pipeline.

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