Jiangsu Nhwa Pharmaceutical Co., Ltd. (002262.SZ) has announced that it recently received the Drug Clinical Trial Approval Notice issued by the National Medical Products Administration for its Class 1 chemical drug, NH302 Injection, and will commence clinical trials in the near future.
NH302 is a peripherally selective Kappa receptor agonist. Preclinical trial results indicate that NH302 exhibits strong agonistic activity on Kappa receptors, demonstrating significant analgesic effects across multiple pain animal models, with a low effective dose and prolonged duration of action. It also features a wide sedation safety window, positioning it as a promising therapeutic candidate for acute pain management with distinct clinical advantages.